I would get the kitty spayed. If she has kittens, they most probably will also be positive and most kittens born with leukemia do not have a very long life - they usually succumb within a year or two, if not sooner, to anemia or lymphoma, especially tumors in the chest area. At this time of year thousands of perfectly healthy kittens are being euthanized in pounds all over the country, so it does not make sense to bring more kittens into the world, especially kittens for whom it will be difficult at best to find homes for, and whose prognosis will probably be poor.
The mama cat might not fare well after the spay - occasionally the anesthesia stresses the cat and brings out the leukemia, but not always right away, and in most cases the cat is not affected by the spay. If she contracted leuk as a young adult or adult, not as a tiny kitten, her chances of living a reasonable length of time are quite good, especially with careful care. Good luck, whatever you decide. Have you listed her on our adoption section?
