Hi Freesurfers-

I was trying to run freesurfer on a study template and was having
major problems with pial surface generation. Orig and Main surfaces
seem to be ok, but there are major missing chinks in pial surface.
Just to give some background, the template was being using for
Diffeomorphic Image Registration, so it is a very unique volume.I know
it is likely it is an intensity value issue.I wondered what folks have
done previously to correct similar issues?

It appears to be across a massive proportion of the brain, so
correcting by hand (by altering intensity values seems a bit labor
intensive and perhaps questionable in terms of reliability). I also
thought of trying to rerun some of the initial preprocessing
(autorecon1 + 2) with some more 'expert settings'. Initially, I was
running with no skull strip and no n3 flag (b/c the template has
already been skull-stripped and massive preprocessed), but was looking
for some additional advice and guidance.

Any thoughts or suggestions would be greatly appreciated.

Best,
jamie.




-- 
Jamie L. Hanson
Waisman Laboratory for Brain Imaging & Behavior | Child Emotion Research Lab
University of Wisconsin - Madison
1500 Highland Avenue
Madison, WI 53706
***Please note my new email: [EMAIL PROTECTED]
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