for what it's worth we label the cc now explicitly in the aseg, which is certainly more accurate than the aparc used to be.

Thanks for the detailed answer though Carl!

Bruce
On Mon, 8 Sep 2008 [EMAIL PROTECTED] wrote:


Hi Dara,

You can certainly use either one as Doug says, but depending on your
purposes, one or the other may have some virtues.  2005 consists of
discrete sulcal and gyral labels with traditional anatomical names so
there are a lot more labels (which is why Doug describes it as very
detailed), whereas aparc in general collapses these into summary regions.

But it is not a a simple case of lumper vs splitter....For instance it
seems that

Aparc divides the cingulate into rostral anterior, caudal anterior,
posterior cingulate whereas in aparc 2005 it is lumped into one cingulate
label

Aparc shows the corpus c. nicely (I think there may even be a
subparcellation available in development) whereas the cc is lost in the
medial wall in 2005.

Aparc differentiates the pars orbitalis nicely on the orbital surface from
the rest of the ofc, aparc 2005 does not — possibly of interest to someone
who is looking at ventrolateral pfc and its neighbors

Aparc includes in its lateral ofc label everything lateral to the rectus
gyrus,  including the central ofc and the (unlabeled) transverse sulcus
neither of which would be understood as being in the lateral ofc as that
term is typically used today.

Aparc 2005 shows a view that nicely differentiates the rectus gyrus on
sagital section from the adjoining, whereas aparc lumps a broad territory
into “medial  OFC”

Aparc 2005 includes parcellation of the Insula, aparc does not and it is
lost in the unknown medial wall (there has been talk of fixing this but is
this real, Bruce or Doug?)

Perhaps what we need is a “best of aparc and aparc 2005”.

For surfing purposes you can also “fool” tksurfer into showing you the
names of the (typically more more detailed) 2005 parcellations while
viewing the brain labeled with the aparc labels which at times have more
detail — though I have never asked Doug if this will always work
correctly.

If others have discovered pros and cons in other regions, please share.

Best,


Carl



Carl E. Schwartz, M.D.
Harvard Medical School
Director, Developmental Neuroimaging & Psychopathology Laboratory
Psychiatric Neuroscience Program
Massachusetts General Hospital
tel 617-726-8965
fax 617-726-4078


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