For a two factor GLM analysis with two levels, I'm uncertain as to why the Freesurfer GLM measurement of the interaction effect of say, group and gender, is a t-test and not an F-test. In my case, my factors are group (healthies vs patients) and gender (male vs female). For a 2x2 two-way ANOVA analysis, the measurement of an interaction is always an F-test.
For example, on the following Freesurfer FSGD Wiki page (Four Groups (Two Factors/Two Levels), No Covariates) http://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf4G0V under Contrast 7, it claims the gender-x-handedness is a t-test. Is this contrast a t-test or actually an F-test? Thanks, Chris
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