Hi!

Ok! That would be a good improvement :)

Thanks to both!

Cheers,
Andreia





Citando Douglas N Greve <gr...@nmr.mgh.harvard.edu>:

> Actually, you are right! Most of the non-gray matter structures in the
> medial wall are zeroed out, but the part that goes through the hippo and
> amygdala are non-zero. As Mike points out, this is going to be a very
> small portion of the total cortical volume, but we'll find a way to
> remove it.
> doug
>
> _andre...@sapo.pt wrote:
>> Hi Michael and Doug,
>>
>> Michael:
>> "As you noted, the surfaces bisect the hippocampus and amygdala, so the
>> small amount of tissue outside the pial surface is not included in the
>> surface based measures of total GM volume.  Compared to the overall
>> variation in brain size, this should be inconsequential.
>>
>> cheers,
>> -MH"
>>
>> I got a little confused with your answer. The calculation is
>> everything inside the pial surface - everything inside the wm surface.
>> What is outside is half hippocampus/amygdala and is not included, ok.
>> But the other halves are inside the surfaces, being then included, right?
>>
>> Doug:
>>
>> If the thickness was 0 in those areas that would make sense. But do
>> the surfaces "have" the information that in those regions the
>> structures are hippocampus and amygdala?
>>
>> I checked if the thickness was 0 and from what I'm understanding it is
>> 5mm. What I did was to open tkmedit with aparc+aseg and open tksurfer
>> (for both hemispheres). Then, I used the buttons "Save point" and "Go
>> to saved point" to go from tkmedit to tksurfer. What happened was that
>> when the point was located in the hippocampus or amygdala in tkmedit
>> it had a correspondence in tksurfer in regions which have a thickness
>> value.
>>
>> Please see figures in attachement (green arrows are amygdala poinst
>> and blue arrows are hippocampus points)
>>
>> Am I missing something?
>>
>> Thank you,
>> Andreia
>>
>>
>>
>>
>> Citando Douglas N Greve <gr...@nmr.mgh.harvard.edu>:
>>
>>> Hi Andreia, I don't think this is a problem for the GM volume (ie, parts
>>> of the amyg or hippo getting counted twice). The thickness should be 0
>>> in those areas, so they should not contribute to GM volume. The
>>> computation of the WM volume is done in a different way (still surface
>>> based) but automatically excludes subcortical structures.
>>> doug
>>>
>>> _andre...@sapo.pt wrote:
>>>> Hello,
>>>>
>>>> Recalling these emails:
>>>>
>>>> "The methods are somewhat different. For the value in the aseg.stats
>>>> table, the method is to compute the total volume inside the pial
>>>> surface
>>>> and subtract the total volume inside the white surface. For
>>>> mris_anatomical_stats, the method is to compute the thickness times
>>>> area
>>>> of each vertex. This method will probably underestimate the total
>>>> volume
>>>> because it uses the area of the white surface when it should use the
>>>> area of the surface in the middle between the white and pial surfaces.
>>>> I've added this to the list of known issues on our release page.
>>>>
>>>> doug
>>>>
>>>> Alexopoulos, Dimitrios wrote:
>>>>
>>>>> I have generated surfaces using the the centos4 build (version 5.0)
>>>>> and want to confirm that my surface-based GM and WM volumes are
>>>>> correct.
>>>>> For the surface-based GM calculation I originally used
>>>>> 'mris_anatomical_stats -l lh.cortex.label subjectID hemi'
>>>>> (run from within the 'label' subdirectory) and for WM i used
>>>>> 'mris_wm_volume subjectID hemi' (run from within
>>>>> the 'surf' subdirectory).
>>>>> When I add the calculated left/right cortical volumes, I get a total
>>>>> that is different from what is output in
>>>>> the 'aseg.stats' file, which in version 5.0 is noted to contain
>>>>> total surface-based GM volume
>>>>> (Cortex, CortexVol: Total cortical gray matter volume (based on
>>>>> surface-stream).
>>>>>  What are the correct GM and WM surface-based volumes?
>>>>> Thanks. Jim"
>>>>>
>>>>
>>>>
>>>> I question came up to me:
>>>>
>>>> The surfaces in the hippocampus/amygdala are inaccurate and should be
>>>> ignored. However, in version 5.0 the cortical volume is surface-based,
>>>> thus it takes into account the surfaces in the hippocampus/amygdala,
>>>> is this correct?
>>>>
>>>> If so, it is expected that an error is introduced in the surface-based
>>>> calculation of cortical volume. Has anyone checked the influence of
>>>> this error? Or FS compensates for the inaccuracy of the surface
>>>> estimation of these regions somehow?
>>>>
>>>> Thanks!
>>>>
>>>> Andreia
>>>>
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>>>>
>>>>
>>>>
>>>
>>> --
>>> Douglas N. Greve, Ph.D.
>>> MGH-NMR Center
>>> gr...@nmr.mgh.harvard.edu
>>> Phone Number: 617-724-2358
>>> Fax: 617-726-7422
>>>
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>>
>>
>> ------------------------------------------------------------------------
>>
>>
>> ------------------------------------------------------------------------
>>
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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