Hi, In our functional MRI studies, we co-registration the functional images to anatomical scans (a part of preproc-sess routine in version 5) before measuring the contrasts. But for one of our studies, a reviewer has asked if a “non-rigid image registration” would change results when we are assessing activity within artifact-prone brain areas (e.g. anterior temporal areas).
As far as I know, freesurfer registration works fine and even in this study, we have found very strong activity/contrast within anterior tempotal lobe. But I was wondering whether you have tested this possibility or not. If yes, then I appreciate if you can introduce me a reference (published article) to support our answer. Regards -- Shahin Nasr PhD in Cognitive Neuroscience Martinos Imaging Center, MGH Harvard Medical School
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