Hi Doug and others, Thanks Doug. All the best. 2013-12-20
Rujing Zha 发件人：Douglas N Greve <gr...@nmr.mgh.harvard.edu> 发送时间：2013-12-20 00:11 主题：Re: [Freesurfer] mri_glmfit error 收件人："Rujing Zha"<charujing...@163.com> 抄送："freesurfer"<freesurfer@nmr.mgh.harvard.edu> On 12/18/2013 11:14 PM, Rujing Zha wrote: > Hi Doug and others, > Thanks Doug. > For the 2nd problem: I understand orthogonalization between nuisance > variables. I just want to test the difference between two group mean > pial thickness controling the age and edu (if it is necessary to > control the age and sex). So I guess I have two option: one: I can > select one of them discarding the other one in the fsgd. the other > one: I select both of them, and ignoring the high correlation. > For the 3rd problem: As I just want to know the difference between 2 > group pial thickness controling some other factors which may explain > my result, so I guess I just donot consider the sex as a nuisance factor. > Is that appropriate? I don't know. It is not a question for me to answer since it depends on the data. > There is a new problem for me: > I also want to do a partial analysis between pial thickness analysis > and behavior score. The numbers of class in fsgd file are the same as > this one except adding another colume for the score. Is this correct? Yes > Thanks. > All the best. > 2013-12-19 > ------------------------------------------------------------------------ > /Rujing Zha/ > ------------------------------------------------------------------------ > *发件人：*Douglas Greve <gr...@nmr.mgh.harvard.edu> > *发送时间：*2013-12-19 11:34 > *主题：*Re: [Freesurfer] mri_glmfit error > *收件人：*"Rujing Zha"<charujing...@163.com> > *抄送：*"freesurfer"<freesurfer@nmr.mgh.harvard.edu> > > On 12/18/13 10:26 PM, Rujing Zha wrote: >> Hi Doug and others, >> Thanks Doug. >> I modifiled my number of class in the fsgd which can be got in the >> attachment. >> And I am confused with 3 problems: >> 1st: Is what I modified proper? > Yes >> 2nd: How can I deal with my high correlation between age and edu? > If they are nuisance variables, then you could orthogonalize one with > respect to the other. If you really want to test for a difference in > groups for the age slope or the edu slope, then there is nothing you > can do except get more subjects. >> 3rd: Is it necessary to tell mri_glmfit to distinguish which subject >> is female or male in each class if dividing all subjects into 2 >> classes (i.e con and IA )? > If you only have con and IA, you cannot have a gender factor. If you > think that a gender factor is really necessary, then you need to get > more females. > doug > >> Thanks in advance. >> All the best. >> 2013-12-19 >> ------------------------------------------------------------------------ >> /Rujing Zha/ >> ------------------------------------------------------------------------ >> *发件人：*Douglas N Greve <gr...@nmr.mgh.harvard.edu> >> *发送时间：*2013-12-19 04:59 >> *主题：*Re: [Freesurfer] mri_glmfit error >> *收件人：*"freesurfer"<freesurfer@nmr.mgh.harvard.edu> >> *抄送：* >> Could be several things. You only have two IA_female and and only 3 >> con_female. Also, the age and edu are highly correlated. I would try >> creating a single IA group with males and females and a single con group >> doug >> On 12/18/2013 11:21 AM, Rujing Zha wrote: >> > Hi all, >> > I try to run mri_glmfit, but it export >> > "ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 >> > -------------------------------- >> > Possible problem with experimental design: >> > Check for duplicate entries and/or lack of range of >> > continuous variables within a class.". >> > I upload the data in the attachment, and the glmfit_output is the >> > standard output of the "mri_glmfit". >> > Thanks. >> > All the best. >> > 2013-12-19 >> > ------------------------------------------------------------------------ >> >> > /Rujing Zha/ >> > >> > >> > _______________________________________________ >> > Freesurfer mailing list >> > Freesurfer@nmr.mgh.harvard.edu >> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >> -- >> Douglas N. Greve, Ph.D. >> MGH-NMR Center >> gr...@nmr.mgh.harvard.edu >> Phone Number: 617-724-2358 >> Fax: 617-726-7422 >> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting >> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 >> www.nmr.mgh.harvard.edu/facility/filedrop/index.html >> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ >> _______________________________________________ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >> The information in this e-mail is intended only for the person to whom it is >> >> >> addressed. If you believe this e-mail was sent to you in error and the >> e-mail >> >> contains patient information, please contact the Partners Compliance >> HelpLine at >> >> http://www.partners.org/complianceline . If the e-mail was sent to you in >> error >> >> but does not contain patient information, please contact the sender and >> properly >> >> dispose of the e-mail. > -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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