Definitely #2. You should use the xhemi tools 
http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi
First run them through recon-all as normal, then follow the steps on the 
wiki. Contact the list again to get instructions for the final analysis.

doug


On 02/13/2014 08:23 AM, Paola Valsasina wrote:
>
> Dear List,
>
> we are starting the analysis of cortical thickness for a group of 
> patients who have only one side affected. The majority of patients 
> have the left hemisphere affected, but some patients have the right 
> hemisphere affected. In order to do a group analysis, we would like to 
> flip the images of some patients, so that the affected side is left 
> for all subjects.
>
> Which is the best way to do this:
>
> 1)flip the 001.mgz volume and perform the entire recon-all pipeline 
> with flipped images;
>
> or
>
> 2)perform the recon-all pipeline with the non-flipped volumes and flip 
> only the final surfaces for statistical purposes?
>
> Thank you for any suggestion
>
> Kind regards
>
> Paola
>
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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