Hi Bruce,

I was having issues with the part after that, that is how to calculate the
average thickness of those bins, after I create them. Thanks again
Best,
Panos

> Hi Panos
>
> no, mris_anatomical_stats won't do it. I would map the average thickness
> to fsaverage coords, then load that into matlab and go from there using
> the [xyz] coords of fsaverage for the binning, which is pretty much
> MNI305
>
> cheers
> Bruce
> On Tue, 13 May 2014, pfot...@nmr.mgh.harvard.edu wrote:
>
>> Hi Bruce,
>>
>> Sorry, I had a last follow up question. I just realized that the
>> resulting
>> bins will be in the fsaverage space, and hence I wouldn't be able to use
>> mris_anatomical_stats to calculate the average thickness of the bins,
>> since the fsaverage "subject" does not have a wm.mgz file. Did you have
>> another way in mind to calculate the thickness of each bin, or do you
>> believe that mris_anatomical stats should do the trick with a specific
>> flag?
>>
>> Thanks a ton,
>> Panos
>>
>>> Hi Bruce,
>>>
>>> I see, that's really helpful, thank you!
>>>
>>> Best,
>>> Panos
>>>
>>>
>>>> Hi Panos
>>>>
>>>> I would make an average thickness map in fsaverage space, then in
>>>> matlab
>>>> divvy up the a-p direction into bins (say 100 of them) and compute the
>>>> average in each bin based on the a/p coordinate
>>>>
>>>> cheers
>>>> Bruce
>>>> On Tue, 13 May 2014,
>>>> pfot...@nmr.mgh.harvard.edu wrote:
>>>>
>>>>> Hi Bruce,
>>>>>
>>>>> Just to clarify, when you say "average the thickness along each A/P
>>>>> coordinate" do you mean by looking up at the average cortical
>>>>> thickness
>>>>> of
>>>>> each parcellation and then calculating their average from P->A, or is
>>>>> there another way to find the average thickness of each slice and
>>>>> then
>>>>> see
>>>>> how that average changes from P->A?
>>>>> Thanks again for your time,
>>>>> Panos
>>>>>
>>>>>> I see. Then measure the thickness normally, then see how it changes
>>>>>> in
>>>>>> those directions. You could average the thickness along each A/P
>>>>>> coordinate
>>>>>> - that wouldn't be a problem. You just don't want to measure it that
>>>>>> way
>>>>>>
>>>>>> cheers
>>>>>> Bruce
>>>>>>
>>>>>>
>>>>>> On Mon, 12 May 2014,
>>>>>> pfot...@nmr.mgh.harvard.edu wrote:
>>>>>>
>>>>>>> Hi Bruce,
>>>>>>>
>>>>>>> Thank you for your reply. I was interested in looking how the
>>>>>>> thickness
>>>>>>> changes from the posterior to the anterior side of the brain and
>>>>>>> vice
>>>>>>> versa (the thickness gradient).
>>>>>>>
>>>>>>> Thank you again for your time!
>>>>>>> Panos
>>>>>>>
>>>>>>>
>>>>>>>> Hi Panos
>>>>>>>>
>>>>>>>> it would certainly be possible to make that measurement, but it
>>>>>>>> wouldn't
>>>>>>>> tell you anything biologically interesting. Why would you want to
>>>>>>>> do
>>>>>>>> such
>>>>>>>> a
>>>>>>>> thing? It will reflect the (arbitrary) image slice orientation and
>>>>>>>> not
>>>>>>>> the
>>>>>>>> brain.
>>>>>>>>
>>>>>>>> cheers
>>>>>>>> Bruce
>>>>>>>>
>>>>>>>>
>>>>>>>> On Mon, 12 May 2014, pfot...@nmr.mgh.harvard.edu wrote:
>>>>>>>>
>>>>>>>>> Hi FS experts,
>>>>>>>>>
>>>>>>>>> I was wondering whether it would be possible to measure the
>>>>>>>>> average
>>>>>>>>> cortical thickness at a specific slice (either axial, coronal, or
>>>>>>>>> sagittal). I read in Bruce's paper: "Measuring the thickness of
>>>>>>>>> the
>>>>>>>>> human
>>>>>>>>> cerebral cortex from magnetic resonance images" that "Measuring
>>>>>>>>> the
>>>>>>>>> thickness from the coronal slice at the point indicated by the
>>>>>>>>> green
>>>>>>>>> cross
>>>>>>>>> would result in an estimate in excess of 1 cm." Is that always
>>>>>>>>> the
>>>>>>>>> case,
>>>>>>>>> or has there been a way to bypass that issue?
>>>>>>>>>
>>>>>>>>> Thank you for your time,
>>>>>>>>> Panos
>>>>>>>>> _______________________________________________
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>>>>>>>>>
>>>>>>>>>
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>>>>>>>>
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