Hi Will

it looks like there is incomplete myelination, which is probably part of your problem. You could try manually adjusting the transform in tkregister2

cheers
Bruce
On Thu, 28 Jan 2016, will brown wrote:

Hi Bruce,
I've attached a shot of the misalignment as seen in freeview.
Yes the original images were DICOM created in Siemens machine T1, 0.8 slice
thickness, can provide all DICOM tags if needed.

Thanks,
Will


On Tue, Jan 26, 2016 at 6:00 AM, <[email protected]>
wrote:
      Send Freesurfer mailing list submissions to
              [email protected]

      To subscribe or unsubscribe via the World Wide Web, visit
             
      https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      or, via email, send a message with subject or body 'help' to
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      You can reach the person managing the list at
              [email protected]

      When replying, please edit your Subject line so it is more
      specific
      than "Re: Contents of Freesurfer digest..."


      Today's Topics:

         1. Re: mritotal failed - help with manual registration (Bruce
      Fischl)
         2. recon -all errors (Jasmin Alves)
         3. Re: Processing .mnc files (Ankita Chatterjee)
         4. Re: Processing .mnc files (Bruce Fischl)
         5. Re: mri_binarize --i sig.cluster.mgh --min 1.3 --o
            thresholded.mgh 1.3 = -log10(.05) (Erik Lindberg)
         6. hippocampal subfields - multispectral segmentation       
      with FLAIR
            (Luigi Antelmi)
         7. Re: hippocampal subfields - multispectral segmentation   
      with
            FLAIR (Eugenio Iglesias)
         8. Re: recon -all errors (Bruce Fischl)
         9. Re: mri_binarize --i sig.cluster.mgh --min 1.3 --o
            thresholded.mgh 1.3 = -log10(.05) (Bruce Fischl)
        10. Re: mri_binarize --i sig.cluster.mgh --min 1.3 --o
            thresholded.mgh 1.3 = -log10(.05) (Erik Lindberg)
        11. Re: mri_binarize --i sig.cluster.mgh --min 1.3 --o
            thresholded.mgh 1.3 = -log10(.05) (Bruce Fischl)
        12. FDR map: hide very little cluster ([email protected])
        13. [All] position available immediately (Bruce Fischl)
        14. Re: mri_binarize --i sig.cluster.mgh --min 1.3 --o
            thresholded.mgh 1.3 = -log10(.05) (Douglas Greve)
        15. Re: FDR map: hide very little cluster (Douglas Greve)
        16. R: Re:  FDR map: hide very little cluster
      ([email protected])
        17. R: Re:  FDR map: hide very little cluster
      ([email protected])
        18. Re: R: Re: FDR map: hide very little cluster (Douglas N
      Greve)
        19. R:  R: Re:  FDR map: hide very little cluster
      ([email protected])
        20. Re: R: R: Re: FDR map: hide very little cluster (Douglas N
      Greve)
        21. R: Re:  R: Re: FDR map: hide very little cluster
            ([email protected])


      ----------------------------------------------------------------------

      Message: 1
      Date: Sun, 24 Jan 2016 18:58:54 -0500 (EST)
      From: Bruce Fischl <[email protected]>
      Subject: Re: [Freesurfer] mritotal failed - help with manual
              registration
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <[email protected]>
      Content-Type: text/plain; charset=US-ASCII; format=flowed

      Hi Will

      can you take the same images with freeview and send them along?
      Also:
      tell us a bit about your images. What format did they start in?
      Were they
      dicoms?

      Bruce

      On Mon, 25 Jan 2016, will brown wrote:

      > Hi all,
      > After attempting recon-all I received the error "mritotal
      failed, see
      > transforms/talairach.log" etc which I understand may have
      something to do
      > with bad output from registration. I've checked orig.mgz which
      does look out
      > of line - the orientation is off so that it appears the
      subject has their
      > head tilted off to one side (see Image1.jpg).
      >
      > I have tried to fix this manually with the help of this
      tutorial:
      >
      > http://freesurfer.net/fswiki/FsTutorial/Talairach_freeview
      >
      > Hovever, the "movable" blurry image that I'm trying to line up
      with my
      > subjects image does not match the coronal, sagittal or
      horizontal views,
      > e.g. when I click "coronal" my subject is displayed correctly
      but the
      > movable image is displayed horizontally (see Image2.jpg and
      Image3.jpg).
      >
      > Am I missing something obvious? (and am I even on the right
      track given this
      > error?)
      >
      > Thanks in advance for any help.
      >
      > Cheers,
      > Will
      >
      >


      ------------------------------

      Message: 2
      Date: Sun, 24 Jan 2016 18:36:11 -0800
      From: Jasmin Alves <[email protected]>
      Subject: [Freesurfer] recon -all errors
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <CACuamQ5whG9jjQLPvD5Hq4BAF+=C4ZvrACb3PrF2+KAx=aLN=q...@mail.gmail.com>
      Content-Type: text/plain; charset="utf-8"

      Hello Freesurfer,

      I am trying to learn freesurfer and ran into the following
      issues below
      running the recon -all command.

      FREESURFER_HOME: /Applications/freesurfer

      Build stamp: freesurfer-Darwin-lion-stable-pub-v5.3.0

      Kernel info: Darwin 14.5.0 x86_64

        1)

      joya

       2)

       Jasmins-MacBook-Pro:subjects jasminalves$ recon-all -i
      T1_original_joya.nii -subject joya -all &


      3)

      [1] 12300

      Jasmins-MacBook-Pro:subjects jasminalves$ mkdir:
      /Applications/freesurfer/subjects/joya: Permission denied

      mkdir: /Applications/freesurfer/subjects/joya/scripts:
      Permission denied

      mkdir: /Applications/freesurfer/subjects/joya/scripts:
      Permission denied

      cp:
      /Applications/freesurfer/subjects/joya/scripts/build-stamp.txt:
      No such
      file or directory

      cat:
      /Applications/freesurfer/subjects/joya/scripts/build-stamp.txt:
      No
      such file or directory

      INFO: FreeSurfer build stamps do not match

      Subject Stamp:

      Current Stamp: freesurfer-Darwin-lion-stable-pub-v5.3.0

      INFO: SUBJECTS_DIR is /Applications/freesurfer/subjects

      Actual FREESURFER_HOME /Applications/freesurfer

      /Applications/freesurfer/subjects/joya: No such file or
      directory.


      [1]+  Exit 1                  recon-all -i T1_original_joya.nii
      -subject
      joya -a
      Thank you,
      Jasmin

      Jasmin Alves
      Predoctoral Student
      Medical Biology Graduate Program
      University of Southern California
      [email protected]
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      ------------------------------

      Message: 3
      Date: Mon, 25 Jan 2016 03:55:01 +0000
      From: Ankita Chatterjee <[email protected]>
      Subject: Re: [Freesurfer] Processing .mnc files
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <CAGG19OQ=36q5o9qfcotmkx1t4hmdwt6-0htnu+ihvory0lh...@mail.gmail.com>
      Content-Type: text/plain; charset="utf-8"

      Thank you for your help! The process took 22 hours, but it
      completed
      without errors! Now I will start looking at the output to
      analyze.

      I was wondering if it is possible to run 3-4 of the freesurfer
      processes
      like recon-all simultaneously? I will be running these on a Mac
      with 8 Ghz
      of Memory and a 2.66 GHz processor - is that sufficient hardware
      capability
      to run several simultaneous processes?

      Thanks again!
      Ankita

      On Sun, Jan 24, 2016 at 6:41 AM Bruce Fischl
      <[email protected]>
      wrote:

      > nope, keep waiting. Depending on your hardware and how
      different the
      > anatomy is from normal it can take up to a day.
      >
      > as for LGI, check recon-all -help
      > cheers
      > Bruce
      > On Sun, 24 Jan 2016, Ankita
      > Chatterjee wrote:
      >
      > > I ran the command recon-all -all -s t2 -i t1xxxxx.mnc as
      Bruce suggested
      > and
      > > the process took off but has been running for more than 6
      hours and
      > seems to
      > > be not doing anything after the step which reads
      MRISunfold() max_passes
      > = 1
      > > -----------it has a few steps after that, but doesn't say
      that it
      > completed.
      > > The last line reads -
      > > randomSeed 1234. Is it hung? Should I exit the program?
      > >
      > > Thank you for your help!
      > > Ankita
      > >
      > >_______________________________________________
      > Freesurfer mailing list
      > [email protected]
      > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      >
      >
      > The information in this e-mail is intended only for the person
      to whom it
      > is
      > addressed. If you believe this e-mail was sent to you in error
      and the
      > e-mail
      > contains patient information, please contact the Partners
      Compliance
      > HelpLine at
      > http://www.partners.org/complianceline . If the e-mail was
      sent to you in
      > error
      > but does not contain patient information, please contact the
      sender and
      > properly
      > dispose of the e-mail.
      >
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      ------------------------------

      Message: 4
      Date: Sun, 24 Jan 2016 23:11:54 -0500
      From: Bruce Fischl <[email protected]>
      Subject: Re: [Freesurfer] Processing .mnc files
      To: Freesurfer support list <[email protected]>
      Message-ID:
      <[email protected]>
      Content-Type: text/plain; charset="us-ascii"

      Hi Ankita

      Glad it worked :) How many cores do you have? If only 1 there is
      nothing to be gained by running them in parallel. If more than 1
      I think you should be able to fit at least two in that much ram,
      but perhaps someone else can comment? Maybe 3?

      Cheers
      Bruce
      > On Jan 24, 2016, at 10:55 PM, Ankita Chatterjee
      <[email protected]> wrote:
      >
      > Thank you for your help! The process took 22 hours, but it
      completed without errors! Now I will start looking at the output
      to analyze.
      >
      > I was wondering if it is possible to run 3-4 of the freesurfer
      processes like recon-all simultaneously? I will be running these
      on a Mac with 8 Ghz of Memory and a 2.66 GHz processor - is that
      sufficient hardware capability to run several simultaneous
      processes?
      >
      > Thanks again!
      > Ankita
      >
      >> On Sun, Jan 24, 2016 at 6:41 AM Bruce Fischl
      <[email protected]> wrote:
      >> nope, keep waiting. Depending on your hardware and how
      different the
      >> anatomy is from normal it can take up to a day.
      >>
      >> as for LGI, check recon-all -help
      >> cheers
      >> Bruce
      >> On Sun, 24 Jan 2016, Ankita
      >> Chatterjee wrote:
      >>
      >> > I ran the command recon-all -all -s t2 -i t1xxxxx.mnc as
      Bruce suggested and
      >> > the process took off but has been running for more than 6
      hours and seems to
      >> > be not doing anything after the step which reads
      MRISunfold() max_passes = 1
      >> > -----------it has a few steps after that, but doesn't say
      that it completed.
      >> > The last line reads -
      >> > randomSeed 1234. Is it hung? Should I exit the program?
      >> >
      >> > Thank you for your help!
      >> > Ankita
      >> >
      >> >_______________________________________________
      >> Freesurfer mailing list
      >> [email protected]
      >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      >>
      >>
      >> The information in this e-mail is intended only for the
      person to whom it is
      >> addressed. If you believe this e-mail was sent to you in
      error and the e-mail
      >> contains patient information, please contact the Partners
      Compliance HelpLine at
      >> http://www.partners.org/complianceline . If the e-mail was
      sent to you in error
      >> but does not contain patient information, please contact the
      sender and properly
      >> dispose of the e-mail.
      > _______________________________________________
      > Freesurfer mailing list
      > [email protected]
      > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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      ------------------------------

      Message: 5
      Date: Mon, 25 Jan 2016 09:39:53 +0100
      From: Erik Lindberg <[email protected]>
      Subject: Re: [Freesurfer] mri_binarize --i sig.cluster.mgh --min
      1.3
              --o thresholded.mgh 1.3 = -log10(.05)
      To: [email protected]
      Message-ID:
             
      <ca+71yoir4vkpnsoesqxsd7snscbkrtbs7w0wsvd+imnbwav...@mail.gmail.com>
      Content-Type: text/plain; charset="utf-8"

      Dear Douglas and Freesufers,



      You suggested:

      mri_binarize --i sig.cluster.mgh --min 1.3 --o thresholded.mgh
      1.3 =
      -log10(.05)



      I tried this and was expecting that I would get a
      three-dimensional mask in
      which the statistical significant part would be white and the
      rest black.

      This seems not to be the case. While the program is telling me
      that it is
      creating a mask in which x-number of voxels are included I
      cannot see
      anything when I open the thresholded.mgh (in Freeview) Further
      when I look
      at the dimensions of the generated image it seems to have 27307
      ?slices? in
      one direction but only one and 6 slices in the other directions.





      Is this the wrong approach for creating a 3-dimensional mask for
      the region
      with the significant clusters?



      Best

      Eric
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      ------------------------------

      Message: 6
      Date: Mon, 25 Jan 2016 09:43:29 +0100
      From: Luigi Antelmi <[email protected]>
      Subject: [Freesurfer] hippocampal subfields - multispectral
              segmentation    with FLAIR
      To: [email protected]
      Message-ID:
             
      <CA+erP2_y34F-C5r7Uq3=qi7gbvwbttx6xw2rg4sx2fkfyz0...@mail.gmail.com>
      Content-Type: text/plain; charset="utf-8"

      Dear members,

      in our center we are  evaluating whether to introduce a T2 into
      a protocol
      that, among others, already includes a T1 and a FLAIR sequences.

      Our main concern is to to maximize the information-to-duration
      ratio of the
      entire protocol.

      In order to improve the subfields' segmentation we read that it
      is better
      to add a T2 or "other" sequences.

      Will the FLAIR alone (+T1)  can work well as the T2?

      If instead the T2 is preferable, what is the
      coarsest-but-still-informative
      resolution you suggest?

      Thank you for sharing your experience!

      Have a nice day,
      Luigi.
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      ------------------------------

      Message: 7
      Date: Mon, 25 Jan 2016 10:02:11 +0100 (CET)
      From: Eugenio Iglesias <[email protected]>
      Subject: Re: [Freesurfer] hippocampal subfields - multispectral
              segmentation    with FLAIR
      To: Freesurfer support list <[email protected]>
      Message-ID:
      <[email protected]>
      Content-Type: text/plain; charset="utf-8"

      Ciao Luigi,
      I haven't tried FLAIR for images the subfields, but if you sent
      me a high-res FLAIR acquisition of the hippocampus, I could take
      a look.
      If you are doing T2, you could implement the procotol used in
      ADNI: coronal slices with 0.4x0.4 in plane resolution, with 2mm
      slice separation (ideally, you would position the box in an
      slightly oblique positions such that the coronal slices cut the
      hippocampus perpendicularly to it major axis).
      Cheers,
      Eugenio

      Juan Eugenio Iglesias
      Postdoctoral researcher BCBL
      www.jeiglesias.com
      www.bcbl.eu

      Legal disclaimer/Aviso legal/Lege-oharra:
      www.bcbl.eu/legal-disclaimer


      From: "Luigi Antelmi" <[email protected]>
      To: "Freesurfer support list" <[email protected]>
      Sent: Monday, January 25, 2016 9:43:29 AM
      Subject: [Freesurfer] hippocampal subfields - multispectral
      segmentation with FLAIR

      Dear members,

      in our center we are evaluating whether to introduce a T2 into a
      protocol that, among others, already includes a T1 and a FLAIR
      sequences.

      Our main concern is to to maximize the information-to-duration
      ratio of the entire protocol.

      In order to improve the subfields' segmentation we read that it
      is better to add a T2 or "other" sequences.

      Will the FLAIR alone (+T1) can work well as the T2?

      If instead the T2 is preferable, what is the
      coarsest-but-still-informative resolution you suggest?

      Thank you for sharing your experience!

      Have a nice day,
      Luigi.

      _______________________________________________
      Freesurfer mailing list
      [email protected]
      https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


      The information in this e-mail is intended only for the person
      to whom it is
      addressed. If you believe this e-mail was sent to you in error
      and the e-mail
      contains patient information, please contact the Partners
      Compliance HelpLine at
      http://www.partners.org/complianceline . If the e-mail was sent
      to you in error
      but does not contain patient information, please contact the
      sender and properly
      dispose of the e-mail.
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      ------------------------------

      Message: 8
      Date: Mon, 25 Jan 2016 09:33:52 -0500 (EST)
      From: Bruce Fischl <[email protected]>
      Subject: Re: [Freesurfer] recon -all errors
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <[email protected]>
      Content-Type: text/plain; charset="utf-8"

      Hi Jasmin

      you  need to create a directory where you have write permission
      and room
      for the subject reconstruction to be written to, then set the
      SUBJECTS_DIR
      environment variable to point to it. At the moment you are
      trying to use
      the subject directory we distribute, which is in some system
      (and
      read-only) location. You can do this on the command line of
      recon-all via:

      recon-all -sd <path to directory> ...

      cheers
      Bruce


      On Sun, 24 Jan 2016, Jasmin Alves
      wrote:

      > Hello Freesurfer,
      >
      > I am trying to learn freesurfer and ran into the following
      issues below
      > running the recon -all command.?
      >
      > FREESURFER_HOME: /Applications/freesurfer
      >
      > Build stamp: freesurfer-Darwin-lion-stable-pub-v5.3.0
      >
      > Kernel info: Darwin 14.5.0 x86_64
      >
      > ??1)?
      >
      > joya
      >
      > ?2)?
      >
      > ?Jasmins-MacBook-Pro:subjects jasminalves$ recon-all -i
      T1_original_joya.nii
      > -subject joya -all &
      >
      >
      > 3)
      >
      > [1] 12300?
      >
      > Jasmins-MacBook-Pro:subjects jasminalves$ mkdir:
      > /Applications/freesurfer/subjects/joya: Permission denied
      >
      > mkdir: /Applications/freesurfer/subjects/joya/scripts:
      Permission denied
      >
      > mkdir: /Applications/freesurfer/subjects/joya/scripts:
      Permission denied
      >
      > cp:
      /Applications/freesurfer/subjects/joya/scripts/build-stamp.txt:
      No such
      > file or directory
      >
      > cat:
      /Applications/freesurfer/subjects/joya/scripts/build-stamp.txt:
      No such
      > file or directory
      >
      > INFO: FreeSurfer build stamps do not match
      >
      > Subject Stamp:?
      >
      > Current Stamp: freesurfer-Darwin-lion-stable-pub-v5.3.0
      >
      > INFO: SUBJECTS_DIR is /Applications/freesurfer/subjects
      >
      > Actual FREESURFER_HOME /Applications/freesurfer
      >
      > /Applications/freesurfer/subjects/joya: No such file or
      directory.
      >
      >
      > [1]+? Exit 1? ? ? ? ? ? ? ? ? recon-all -i
      T1_original_joya.nii -subject
      > joya -a
      >
      > Thank you,Jasmin
      >
      > Jasmin AlvesPredoctoral Student?
      > Medical Biology Graduate Program?
      > University of Southern California
      > [email protected]?
      >
      >
      >

      ------------------------------

      Message: 9
      Date: Mon, 25 Jan 2016 09:35:11 -0500 (EST)
      From: Bruce Fischl <[email protected]>
      Subject: Re: [Freesurfer] mri_binarize --i sig.cluster.mgh --min
      1.3
              --o thresholded.mgh 1.3 = -log10(.05)
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <[email protected]>
      Content-Type: text/plain; charset="utf-8"

      Hi Erik

      what is the dimensionality of sig.cluster.mgh? You can tell this
      with
      mri_info. It is problaby a surface overlay (so nvertices in one
      dimension),
      and can't be viewed in the volume but only on the surface.

      cheers
      Bruce


      On Mon, 25 Jan 2016, Erik Lindberg wrote:

      >
      > Dear Douglas and Freesufers,
      >
      > ?
      >
      > You suggested:
      >
      > mri_binarize --i sig.cluster.mgh --min 1.3 --o thresholded.mgh
      1.3 =
      > -log10(.05)
      >
      > ?
      >
      > I tried this and was expecting that I would get a
      three-dimensional mask in
      > which the statistical significant part would be white and the
      rest black.
      >
      > This seems not to be the case. While the program is telling me
      that it is
      > creating a mask in which x-number of voxels are included I
      cannot see
      > anything when I open the thresholded.mgh (in Freeview) Further
      when I look
      > at the dimensions of the generated image it seems?to have
      27307 ?slices? in
      > one direction but only one and 6 slices in the other
      directions.
      >
      >
      >
      > ?
      >
      > Is this the wrong approach for creating a 3-dimensional mask
      for the region
      > with the significant clusters?
      >
      > ?
      >
      > Best
      >
      > Eric
      >
      >
      >

      ------------------------------

      Message: 10
      Date: Mon, 25 Jan 2016 16:22:28 +0100
      From: Erik Lindberg <[email protected]>
      Subject: Re: [Freesurfer] mri_binarize --i sig.cluster.mgh --min
      1.3
              --o thresholded.mgh 1.3 = -log10(.05)
      To: [email protected]
      Message-ID:
             
      <CA+71YOg=553f5vkcplp5ghmh5-8z6dcjdssm5qu9e8dipg-...@mail.gmail.com>
      Content-Type: text/plain; charset="utf-8"

      Dear Bruce and Freesurfers,


      I probably then go about this in the wrong way. My aim is to
      create a
      binary mask for regions that I found differences in - in a
      group-comparison. I then want to export the mask so I can use it
      as
      seed area in an fMRI analysis.


      Can this be done


      Thanks
      Eric



      Hi Erik


      what is the dimensionality of sig.cluster.mgh? You can tell this
      with mri_info.
      It is problaby a surface overlay (so nvertices in one
      dimension), and can't
      be viewed in the volume but only on the surface.

      cheers
      Bruce
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      ------------------------------

      Message: 11
      Date: Mon, 25 Jan 2016 10:27:26 -0500 (EST)
      From: Bruce Fischl <[email protected]>
      Subject: Re: [Freesurfer] mri_binarize --i sig.cluster.mgh --min
      1.3
              --o thresholded.mgh 1.3 = -log10(.05)
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <[email protected]>
      Content-Type: text/plain; charset="utf-8"

      yes, but do you want to do the fMRI analysis on the surface or
      in the
      volume? There are lots of advantages to doing it on the surface.
      If your
      sig.cluster.mgh was a surface overlay then the threholded.mgh
      might be
      exactly what you want. Load it on an inflated surface and take a
      look

      cheers
      Bruce


      On Mon, 25 Jan 2016, Erik Lindberg wrote:

      >
      > Dear Bruce and Freesurfers,
      >
      > I probably then go about this in the wrong way. My aim is to
      create a binary
      >  mask for regions that I found differences in - in a
      group-comparison. I the
      > n want to export the mask so I can use it as seed area in an
      fMRI analysis.
      >
      > Can this be done
      >
      > Thanks
      > Eric
      >
      > Hi Erik
      >
      > what is the dimensionality of sig.cluster.mgh? You can tell
      this
      > with?mri_info. It is problaby a surface overlay (so nvertices
      in one
      > dimension),?and can't be viewed in the volume but only on the
      surface.
      >
      > cheers
      > Bruce
      >
      >
      >

      ------------------------------

      Message: 12
      Date: Mon, 25 Jan 2016 16:39:52 +0100 (CET)
      From: <[email protected]>
      Subject: [Freesurfer] FDR map: hide very little cluster
      To: [email protected]
      Message-ID:
             
      <1004043139.1736401453736392850.javamail.ht...@fep-webmail-18.iol.local>

      Content-Type: text/plain; charset="utf-8"

      Hi list,please, could you help me because from several days I'm
      trying to have a solution.I have performed a seed-based fcMRI
      analysis by FAST.After mri_glmfit, I have obtained a sig.nii.gz
      which contains uncorrected results.I have corrected by FDR using
      the graphical interface provided in tksurfur. The FDR corrected
      contains some very small areas (<5-10 voxels) which I would like
      to hide in order to  present a more clear map. How is possible
      to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I should have a CSD file. But this file could be
      also produced when FDR correction is applied? I'm very
      confused.Thank you very much for your work.Kind regards.
      Stefano
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      ------------------------------

      Message: 13
      Date: Mon, 25 Jan 2016 10:47:39 -0500 (EST)
      From: Bruce Fischl <[email protected]>
      Subject: [Freesurfer] [All] position available immediately
      To: [email protected]
      Cc: "Dara S. Manoach" <[email protected]>
      Message-ID:
             
      <[email protected]>
      Content-Type: text/plain; charset="utf-8"




      Research?Coordinator Position in Psychiatric Neuroimaging at the
      MGH-Martinos Center:
      ?
      We are looking to hire a college graduate?with at least one year
      of research
      experience and strong organizational and?interpersonal skills as
      a full time
      research?coordinator.??The position involves working on or
      several?projects
      investigating the neural basis and nature of cognitive deficits
      in
      schizophrenia?and autism spectrum?disorder. The techniques
      employed include
      polysomnography?(sleep electroencephaolography), functional
      magnetic
      resonance imaging (fMRI),?magneto- and?electroencephalography
      (MEG/EEG), and
      diffusion tensor imaging?(DTI).??Responsibilities are varied
      and?will
      include conducting overnight sleep studies at the MGH?Clinical
      Research?Center. The coordinator will work closely with the
      Principal
      Investigator, lab?mates, and collaborators on all aspects of the
      research
      projects.?Training in?data acquisition and analysis will be
      provided.??Responsibilities include managing patient studies,
      recruitment,
      screening?and characterization of?participants, maintaining
      accurate
      records, and?assisting with grant applications, human subject
      applications,
      and?publications.??Knowledge of Mac and/or Linux/UNIX?operating
      systems as
      well as some programming experience are an asset, as is a?high
      level of
      comfort with novel computer applications and environments.??We
      use?Matlab
      and/or unix scripting in many?of our analyses. A background in
      psychology,
      statistics, and neuroscience is an?asset.??A mentored research
      project
      is?encouraged.??The candidate must be mature?and responsible
      with excellent
      organizational, interpersonal as well as oral?and written
      communication
      skills.??S/He?must be?able to work independently in a fast-paced
      environment, juggle and?prioritize multiple tasks, feel
      comfortable working
      with clinical and?non-clinical study populations,?working as
      part of a team
      and seek assistance?when appropriate.??This is an
      excellent?research
      opportunity for someone bound for graduate school in
      psychology,?cognitive
      neuroscience, or medicine.??Position is available
      immediately.??A two-year
      commitment is required.??Please submit a resume, writing sample,
      college?transcript (unofficial?is fine) and contact information
      for three
      references to?Dara Manoach <[email protected]>
      Dara S. Manoach, Ph.D.
      Psychiatric Neuroimaging and
      Athinoula A. Martinos Center for Biomedical Imaging
      Massachusetts General Hospital
      Charlestown Navy Yard
      149 13th Street, Room 1.111
      Charlestown, MA 02129
      email:[email protected]
      phone: 617-724-6148
      fax: 617-726-4078
      http://nmr.mgh.harvard.edu/manoachlab

      ??? I am dictating emails. Please excuse typos, word
      substitutions and the
      lack of appropriate capitalization and punctuation. ???

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      _______________________________________________
      All mailing list
      [email protected]
      https://mail.nmr.mgh.harvard.edu/mailman/listinfo/all

      ------------------------------

      Message: 14
      Date: Mon, 25 Jan 2016 11:03:41 -0500
      From: Douglas Greve <[email protected]>
      Subject: Re: [Freesurfer] mri_binarize --i sig.cluster.mgh --min
      1.3
              --o thresholded.mgh 1.3 = -log10(.05)
      To: [email protected]
      Message-ID: <[email protected]>
      Content-Type: text/plain; charset="windows-1252"

      please remember to include previous correspondences. We can't
      remember
      every post ...

      On 1/25/16 3:39 AM, Erik Lindberg wrote:
      >
      > Dear Douglas and Freesufers,
      >
      > You suggested:
      >
      > mri_binarize --i sig.cluster.mgh --min 1.3 --o thresholded.mgh
      1.3 =
      > -log10(.05)
      >
      > I tried this and was expecting that I would get a
      three-dimensional
      > mask in which the statistical significant part would be white
      and the
      > rest black.
      >
      > This seems not to be the case. While the program is telling me
      that it
      > is creating a mask in which x-number of voxels are included I
      cannot
      > see anything when I open the thresholded.mgh (in Freeview)
      Further
      > when I look at the dimensions of the generated image it seems
      to have
      > 27307 ?slices? in one direction but only one and 6 slices in
      the other
      > directions.
      >
      >
      >
      > Is this the wrong approach for creating a 3-dimensional mask
      for the
      > region with the significant clusters?
      >
      > Best
      >
      > Eric
      >
      >
      >
      > _______________________________________________
      > Freesurfer mailing list
      > [email protected]
      > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

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      ------------------------------

      Message: 15
      Date: Mon, 25 Jan 2016 11:10:47 -0500
      From: Douglas Greve <[email protected]>
      Subject: Re: [Freesurfer] FDR map: hide very little cluster
      To: [email protected]
      Message-ID: <[email protected]>
      Content-Type: text/plain; charset="windows-1252"

      Use the --minarea option to mri_surfcluster (not the CSD).

      On 1/25/16 10:39 AM, [email protected] wrote:
      > Hi list,
      > please, could you help me because from several days I'm trying
      to have a solution.
      > I have performed a seed-based fcMRI analysis by FAST.
      > After mri_glmfit, I have obtained a sig.nii.gz which contains
      uncorrected results.I have corrected by FDR using the graphical
      interface provided in tksurfur. The FDR corrected contains some
      very small areas (<5-10 voxels) which I would like to hide in
      order to  present a more clear map. How is possible to do it?I
      have tried with  mri_surfcluster. To have vwsig.nii.gz I should
      have a CSD file. But this file
      > could be also produced when FDR correction is applied? I'm
      very confused.
      > Thank you very much for your work.
      > Kind regards.
      > Stefano
      >
      >
      > _______________________________________________
      > Freesurfer mailing list
      > [email protected]
      > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

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      ------------------------------

      Message: 16
      Date: Mon, 25 Jan 2016 17:21:21 +0100 (CET)
      From: <[email protected]>
      Subject: [Freesurfer] R: Re:  FDR map: hide very little cluster
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <991888114.1746961453738881317.javamail.ht...@fep-webmail-18.iol.local>

      Content-Type: text/plain; charset="utf-8"

      Thanks. But I do not know how I can obtain a corrected
      sig.nii.gz.In this way I have obtained only summary.txt.If I add
      --vwsig vwsig cds file is request.
      Stefano



      ----Messaggio originale----

      Da: Douglas Greve <[email protected]>

      Data: 25-gen-2016 17.10

      A: <[email protected]>

      Ogg: Re: [Freesurfer] FDR map: hide very little cluster






          Use the --minarea option to mri_surfcluster (not the CSD).



          On 1/25/16 10:39 AM, [email protected]
            wrote:



            Hi list,
            please, could you help me because from several days I'm
      trying to have a solution.I have performed a seed-based fcMRI
      analysis by FAST.
            After mri_glmfit, I have obtained a sig.nii.gz which
      contains uncorrected results.I have corrected by FDR using the
      graphical interface provided in tksurfur. The FDR corrected
      contains some very small areas (<5-10 voxels) which I would like
      to hide in order to  present a more clear map. How is possible
      to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I should have a CSD file. But this file
            could be also produced when FDR correction is applied? I'm
      very confused.
            Thank you very much for your work.
            Kind regards.
      Stefano





            _______________________________________________
      Freesurfer mailing list
      [email protected]
      https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer









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      ------------------------------

      Message: 17
      Date: Mon, 25 Jan 2016 17:25:44 +0100 (CET)
      From: <[email protected]>
      Subject: [Freesurfer] R: Re:  FDR map: hide very little cluster
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <922672514.1748331453739144229.javamail.ht...@fep-webmail-18.iol.local>

      Content-Type: text/plain; charset="utf-8"

      Please could you suggest me an example of command line.I'm
      trying from several day without results.Thank you very much.
      Stefano




      ----Messaggio originale----

      Da: Douglas Greve <[email protected]>

      Data: 25-gen-2016 17.10

      A: <[email protected]>

      Ogg: Re: [Freesurfer] FDR map: hide very little cluster






          Use the --minarea option to mri_surfcluster (not the CSD).



          On 1/25/16 10:39 AM, [email protected]
            wrote:



            Hi list,
            please, could you help me because from several days I'm
      trying to have a solution.I have performed a seed-based fcMRI
      analysis by FAST.
            After mri_glmfit, I have obtained a sig.nii.gz which
      contains uncorrected results.I have corrected by FDR using the
      graphical interface provided in tksurfur. The FDR corrected
      contains some very small areas (<5-10 voxels) which I would like
      to hide in order to  present a more clear map. How is possible
      to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I should have a CSD file. But this file
            could be also produced when FDR correction is applied? I'm
      very confused.
            Thank you very much for your work.
            Kind regards.
      Stefano





            _______________________________________________
      Freesurfer mailing list
      [email protected]
      https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer









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      ------------------------------

      Message: 18
      Date: Mon, 25 Jan 2016 11:30:17 -0500
      From: Douglas N Greve <[email protected]>
      Subject: Re: [Freesurfer] R: Re: FDR map: hide very little
      cluster
      To: [email protected]
      Message-ID: <[email protected]>
      Content-Type: text/plain; charset=windows-1252; format=flowed

      just use the FDR thresholded input and set --thmin to 0.5

      On 01/25/2016 11:21 AM, [email protected] wrote:
      > Thanks. But I do not know how I can obtain a corrected
      sig.nii.gz.
      > In this way I have obtained only summary.txt.
      > If I add --vwsig vwsig cds file is request.
      >
      > Stefano
      >
      >     ----Messaggio originale----
      >     Da: Douglas Greve <[email protected]>
      >     Data: 25-gen-2016 17.10
      >     A: <[email protected]>
      >     Ogg: Re: [Freesurfer] FDR map: hide very little cluster
      >
      >     Use the --minarea option to mri_surfcluster (not the CSD).
      >
      >     On 1/25/16 10:39 AM, [email protected] wrote:
      >>     Hi list,
      >>     please, could you help me because from several days I'm
      trying to have a solution.
      >>     I have performed a seed-based fcMRI analysis by FAST.
      >>     After mri_glmfit, I have obtained a sig.nii.gz which
      contains uncorrected results.I have corrected by FDR using the
      graphical interface provided in tksurfur. The FDR corrected
      contains some very small areas (<5-10 voxels) which I would like
      to hide in order to  present a more clear map. How is possible
      to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I should have a CSD file. But this file
      >>     could be also produced when FDR correction is applied?
      I'm very confused.
      >>     Thank you very much for your work.
      >>     Kind regards.
      >>     Stefano
      >>
      >>
      >>     _______________________________________________
      >>     Freesurfer mailing list
      >>     [email protected]
      >>   
       https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      >
      >
      >
      >
      >
      > _______________________________________________
      > Freesurfer mailing list
      > [email protected]
      > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

      --
      Douglas N. Greve, Ph.D.
      MGH-NMR Center
      [email protected]
      Phone Number: 617-724-2358
      Fax: 617-726-7422

      Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
      FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
      www.nmr.mgh.harvard.edu/facility/filedrop/index.html
      Outgoing:
      ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/



      ------------------------------

      Message: 19
      Date: Mon, 25 Jan 2016 17:31:03 +0100 (CET)
      From: <[email protected]>
      Subject: [Freesurfer] R:  R: Re:  FDR map: hide very little
      cluster
      To: [email protected]
      Message-ID:
             
      <2070326566.1749871453739463057.javamail.ht...@fep-webmail-18.iol.local>

      Content-Type: text/plain; charset="utf-8"

      mri_surfcluster --in intercept/sig.nii.gz --hemi rh --sign abs
      --no-adjust --fdr 0.05 --minarea 5 --sum summaryfile --subject
      fsaverage --annot aparc
      produces only summary.txt
      mri_surfcluster --in intercept/sig.nii.gz --hemi rh --sign abs
      --no-adjust --fdr 0.05 --minarea 5 --sum summaryfile --subject
      fsaverage --annot aparc --vwsig vwsig.nii.gzERROR: need csd with
      --vwsig
      How can I obtain/visualize the correspective map to summary.txt?
      Thanks,

      Stefano




      ----Messaggio originale----

      Da: [email protected]

      Data: 25-gen-2016 17.25

      A: "Freesurfer support list"<[email protected]>

      Ogg: [Freesurfer] R: Re:  FDR map: hide very little cluster



      Please could you suggest me an example of command line.I'm
      trying from several day without results.Thank you very much.
      Stefano




      ----Messaggio originale----

      Da: Douglas Greve <[email protected]>

      Data: 25-gen-2016 17.10

      A: <[email protected]>

      Ogg: Re: [Freesurfer] FDR map: hide very little cluster






          Use the --minarea option to mri_surfcluster (not the CSD).



          On 1/25/16 10:39 AM, [email protected]
            wrote:



            Hi list,
            please, could you help me because from several days I'm
      trying to have a solution.I have performed a seed-based fcMRI
      analysis by FAST.
            After mri_glmfit, I have obtained a sig.nii.gz which
      contains uncorrected results.I have corrected by FDR using the
      graphical interface provided in tksurfur. The FDR corrected
      contains some very small areas (<5-10 voxels) which I would like
      to hide in order to  present a more clear map. How is possible
      to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I should have a CSD file. But this file
            could be also produced when FDR correction is applied? I'm
      very confused.
            Thank you very much for your work.
            Kind regards.
      Stefano





            _______________________________________________
      Freesurfer mailing list
      [email protected]
      https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer













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      ------------------------------

      Message: 20
      Date: Mon, 25 Jan 2016 11:35:27 -0500
      From: Douglas N Greve <[email protected]>
      Subject: Re: [Freesurfer] R: R: Re: FDR map: hide very little
      cluster
      To: [email protected]
      Message-ID: <[email protected]>
      Content-Type: text/plain; charset=windows-1252; format=flowed

      use --o instead of --vwsig

      On 01/25/2016 11:31 AM, [email protected] wrote:
      >
      > mri_surfcluster --in intercept/sig.nii.gz --hemi rh --sign abs
      > --no-adjust --fdr 0.05 --minarea 5 --sum summaryfile --subject
      > fsaverage --annot aparc
      >
      >
      > produces only summary.txt
      >
      >
      > mri_surfcluster --in intercept/sig.nii.gz --hemi rh --sign abs
      > --no-adjust --fdr 0.05 --minarea 5 --sum summaryfile --subject
      > fsaverage --annot aparc --vwsig vwsig.nii.gz
      >
      > ERROR: need csd with --vwsig
      >
      >
      > How can I obtain/visualize the correspective map to
      summary.txt?
      >
      >
      > Thanks,
      >
      >
      >
      > Stefano
      >
      >
      >
      >     ----Messaggio originale----
      >     Da: [email protected]
      >     Data: 25-gen-2016 17.25
      >     A: "Freesurfer support
      list"<[email protected]>
      >     Ogg: [Freesurfer] R: Re: FDR map: hide very little cluster
      >
      >     Please could you suggest me an example of command line.
      >     I'm trying from several day without results.
      >     Thank you very much.
      >
      >     Stefano
      >
      >         ----Messaggio originale----
      >         Da: Douglas Greve <[email protected]>
      >         Data: 25-gen-2016 17.10
      >         A: <[email protected]>
      >         Ogg: Re: [Freesurfer] FDR map: hide very little
      cluster
      >
      >         Use the --minarea option to mri_surfcluster (not the
      CSD).
      >
      >         On 1/25/16 10:39 AM, [email protected] wrote:
      >>         Hi list,
      >>         please, could you help me because from several days
      I'm trying to have a solution.
      >>         I have performed a seed-based fcMRI analysis by FAST.
      >>         After mri_glmfit, I have obtained a sig.nii.gz which
      contains uncorrected results.I have corrected by FDR using the
      graphical interface provided in tksurfur. The FDR corrected
      contains some very small areas (<5-10 voxels) which I would like
      to hide in order to  present a more clear map. How is possible
      to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I should have a CSD file. But this file
      >>         could be also produced when FDR correction is
      applied? I'm very confused.
      >>         Thank you very much for your work.
      >>         Kind regards.
      >>         Stefano
      >>
      >>
      >>         _______________________________________________
      >>         Freesurfer mailing list
      >>         [email protected]
      >>       
       https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      >
      >
      >
      >
      >
      >
      >
      > _______________________________________________
      > Freesurfer mailing list
      > [email protected]
      > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

      --
      Douglas N. Greve, Ph.D.
      MGH-NMR Center
      [email protected]
      Phone Number: 617-724-2358
      Fax: 617-726-7422

      Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
      FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
      www.nmr.mgh.harvard.edu/facility/filedrop/index.html
      Outgoing:
      ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/



      ------------------------------

      Message: 21
      Date: Mon, 25 Jan 2016 17:36:35 +0100 (CET)
      From: <[email protected]>
      Subject: [Freesurfer] R: Re:  R: Re: FDR map: hide very little
      cluster
      To: Freesurfer support list <[email protected]>
      Message-ID:
             
      <1961786632.1751471453739795152.javamail.ht...@fep-webmail-18.iol.local>

      Content-Type: text/plain;charset="UTF-8"

      Please give an example of the command line.
      I have performed fdr correction by tksurfer. Should I save that
      map?

      Thanks


      Stefano

      >----Messaggio originale----
      >Da: Douglas N Greve <[email protected]>
      >Data: 25-gen-2016 17.30
      >A: <[email protected]>
      >Ogg: Re: [Freesurfer] R: Re: FDR map: hide very little cluster
      >
      >just use the FDR thresholded input and set --thmin to 0.5
      >
      >On 01/25/2016 11:21 AM, [email protected] wrote:
      >> Thanks. But I do not know how I can obtain a corrected
      sig.nii.gz.
      >> In this way I have obtained only summary.txt.
      >> If I add --vwsig vwsig cds file is request.
      >>
      >> Stefano
      >>
      >>     ----Messaggio originale----
      >>     Da: Douglas Greve <[email protected]>
      >>     Data: 25-gen-2016 17.10
      >>     A: <[email protected]>
      >>     Ogg: Re: [Freesurfer] FDR map: hide very little cluster
      >>
      >>     Use the --minarea option to mri_surfcluster (not the
      CSD).
      >>
      >>     On 1/25/16 10:39 AM, [email protected] wrote:
      >>>     Hi list,
      >>>     please, could you help me because from several days I'm
      trying to have
      a solution.
      >>>     I have performed a seed-based fcMRI analysis by FAST.
      >>>     After mri_glmfit, I have obtained a sig.nii.gz which
      contains
      uncorrected results.I have corrected by FDR using the graphical
      interface
      provided in tksurfur. The FDR corrected contains some very small
      areas (<5-10
      voxels) which I would like to hide in order to  present a more
      clear map. How
      is possible to do it?I have tried with  mri_surfcluster. To have
      vwsig.nii.gz I
      should have a CSD file. But this file
      >>>     could be also produced when FDR correction is applied?
      I'm very
      confused.
      >>>     Thank you very much for your work.
      >>>     Kind regards.
      >>>     Stefano
      >>>
      >>>
      >>>     _______________________________________________
      >>>     Freesurfer mailing list
      >>>     [email protected]
      >>>   
       https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      >>
      >>
      >>
      >>
      >>
      >> _______________________________________________
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      >
      >--
      >Douglas N. Greve, Ph.D.
      >MGH-NMR Center
      >[email protected]
      >Phone Number: 617-724-2358
      >Fax: 617-726-7422
      >
      >Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
      >FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
      >www.nmr.mgh.harvard.edu/facility/filedrop/index.html
      >Outgoing:
      ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
      >
      >_______________________________________________
      >Freesurfer mailing list
      >[email protected]
      >https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
      >
      >
      >The information in this e-mail is intended only for the person
      to whom it is
      >addressed. If you believe this e-mail was sent to you in error
      and the e-mail
      >contains patient information, please contact the Partners
      Compliance HelpLine
      at
      >http://www.partners.org/complianceline . If the e-mail was sent
      to you in
      error
      >but does not contain patient information, please contact the
      sender and
      properly
      >dispose of the e-mail.
      >
      >



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      End of Freesurfer Digest, Vol 143, Issue 39
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