On 04/25/2016 05:28 AM, Jockwitz, Christiane wrote:
>
> Dear FreeSurfer Experts,
>
> I’ve got a question regarding effect sizes: I did a local gyrification 
> analysis using QDEC. I obtained several significant clusters from the 
> analysis for whom I would like to calculate some effect sizes.
>
> On the website/helpline, I saw that fscalc might do this job. 
> Therefore, I would need the gamma.mgh file as well as the rstd.mgh file
>
> 1.The gamma.mgh is supposed to contain the contrast effect size. What 
> coefficient of determination is that?
>
Not sure what you mean. The gamma.mgh is just the value of the contrast 
which is gamma = C*beta, where beta are the regression coefficients, so 
gamma is a type of regression coeff
>
> 2.When the gamma.mgh is divided by the standard deviation (rstd.mgh), 
> I get an output.mgh file, which contains positive as well as negative 
> values ranging from -1 to +1. Since I don’t know which coefficient of 
> determination is used in this calculation, I have problem to interpret 
> these values. What value would be a high/low effect size?
>
Further from zero (pos or neg) would be larger.
>
> 3.I would like to calculate this effect size for my significant 
> cluster instead of vertex-wise effect size. I tried to perform this 
> using mri_segstats. Is that right?
>
Yes, you can do that. What will you do with the result? The final effect 
size value is not meaningful because it is a circular computation (ie, 
it is going to be an overestimate because you have selected voxels that 
had a high effect size to begin with).
>
> Thank you very much in advance.
>
> Best
>
> Christiane
>
>
>
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