Yes, that is possible, but you should see some sort of trend, eg, most 
the ROI should have a certain sign


On 08/24/2016 06:47 PM, miracoo...@gmail.com wrote:
> Thanks doug. Also, let's say I extract the aparcstat table and perform t 
> -test using spss and a ROI become significant, is it possible the significant 
> effect will be lost using GLM surface based?
> Best,
> Paul
>
> Sent from my BlackBerry 10 smartphone.
>    Original Message
> From: Douglas N Greve
> Sent: Wednesday, August 24, 2016 5:39 PM
> To: freesurfer@nmr.mgh.harvard.edu
> Reply To: Freesurfer support list
> Subject: Re: [Freesurfer] GLM surface based cortical thickness analysis vs 
> aparcstat table cortical thickness
>
> One is a map-based/voxel-wise analysis, each voxel is treated
> separately. The aparc stats table is an average over all vertices in the
> ROI. If you have an effect that does goes across the ROI boundary, it
> could be lost in the ROI analysis. On the other hand, the ROI analysis
> may be more powerful because of the averaging across space and fewer
> issues with registration across subject
>
>
> On 08/23/2016 04:59 PM, miracoo...@gmail.com wrote:
>> Hello freesurfer experts,
>> What's the difference between GLM surface based cortical thickness
>> analysis and the cortical thickness analysis performed when using
>> regions extracted from aparcstat table?
>> Best,
>> Paul
>>
>> Sent from my BlackBerry 10 smartphone.
>>
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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