Dear Freesurfer’s experts,

I would have some questions regarding the LME model to be used in longitudinal 
stream:

1) Which are the ratio limits or % of missing timepoints accepted ? (according 
time, I have less and less subjects time points)

2) Is it possible to include patients that would miss the first timepoint but 
got the others ?

3) Considering a group in longitudinal study, which is the number of subjects 
minimal of this group accepted for LME modeling ?

4) Finally, concerning quality control and among a big number of total time 
points, which essential controls are necessary ? (Control of norm.mgz of the 
base, alignment of longitudinal timepoints on base,… ?)

Best regards,
Matthieu


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