You can look here for what stats are available

https://surfer.nmr.mgh.harvard.edu/fswiki/MorphometryStats

There is no one method that is considered the gold standard. Each will 
represent a different hypothesis to test. Eg, if you use whole brain 
volume, then you will be looking at changes with respect to whole brain 
atrophy. If you use eTIV, the whole brain atrophy will be included in 
your measure


On 09/11/2017 01:12 PM, Alexopoulos, Dimitrios wrote:
>
> Hi,
>
> We running FS 5.3 analyses on 2 cohorts (control vs. malnourished 
> adolescents) and I was wonderful what FS measure would be most 
> accurate for normalizing the volumes.
>
> (i.e total GM, total WM, suparatentorial, etc). The eTIV measures are 
> significantly different between the cohorts.
>
> Is eTIV the best way to normalize or perhaps BrainSegVol?
>
> What FS measure gives you total  brain volume?
>
> Jim
>
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