Thanks

In which contrast I must change "1" with "0.25"?
What is the rationale to use 0.25?


Sent from Virgilio Mobile
________________________________

Il 10/10/2017, Douglas N Greve <gr...@nmr.mgh.harvard.edu> ha scritto:

I don't understand what you mean by "where I should use"

I thought I looked through all those contrasts a few weeks ago, no?


On 10/10/2017 04:22 AM, std...@virgilio.it wrote:
> You have suggested to use
> 0 0 0 0 .25 .25 .25 .25
> to look the map where, considering the group differences, the covariate
> predicts the dependent variable (functional connectivity) in 4GV1.
>
> Below I'm reporting the contrast that I have used.
> Please could you check it and suggest correction?
> Could you explain where I should use 0 0 0 0 .25 .25 .25 .25, please?
>
> Thanks
>
> C1) gr1-gr2_intercept 1 -1 0 0 0 0 0 0
> C2 )gr1-gr2_slope 0 0 0 0 1 -1 0 0
> C3) gr1-gr3_intercept 1 0 -1 0 0 0 0 0
> C4) gr1-gr3_slope 0 0 0 0 1 0 -1 0
> C5) gr1-gr4_intercept 1 0 0 -1 0 0 0 0
> C6) gr1-gr4_slope 0 0 0 0 1 0 0 -1
> C7) gr2-gr3_intercept 0 1 -1 0 0 0 0 0
> C8) gr2-gr3_slope 0 0 0 0 0 1 -1 0
> C9) gr2-gr4_intercept 0 1 0 -1 0 0 0 0
> C10) gr2-gr4_slope 0 0 0 0 0 1 0 -1
> C11) gr3-gr4_intercept  0 0 1 -1 0 0 0 0
> C12) gr3-gr4_slope 0 0 0 0 0 0 1 -1
> C13) gr1+gr2-vs-gr3+gr4.intercept 0.5 0.5 -0.5 -0.5 0 0 0 0
> C14) gr1+gr2-vs-gr3+gr4.slope 0 0 0 0 0.5 0.5 -0.5 -0.5
> C15) group.effect.intercept
> 1 -1 0 0 0 0 0 0
> 1 0 -1 0 0 0 0 0
> 1 0 0 -1 0 0 0 0
> C16) group.effect.slope
>> 0 0 0 0 1 -1 0 0
>> 0 0 0 0 1 0 -1 0
>> 0 0 0 0 1 0 0 -1
>
>
>
>
>
>
>
> On 10/6/17 9:24 AM, std...@virgilio.it wrote:
>> Thank you very much.
>> Where I should put 0 0 0 0 .25 .25 .25 .25?
>> Which are the contrast reported below that I should modify?
>>
>> C1) gr1-gr2_intercept 1 -1 0 0 0 0 0 0
>> C2 )gr1-gr2_slope 0 0 0 0 1 -1 0 0
>> C3) gr1-gr3_intercept 1 0 -1 0 0 0 0 0
>> C4) gr1-gr3_slope 0 0 0 0 1 0 -1 0
>> C5) gr1-gr4_intercept 1 0 0 -1 0 0 0 0
>> C6) gr1-gr4_slope 0 0 0 0 1 0 0 -1
>> C7) gr2-gr3_intercept 0 1 -1 0 0 0 0 0
>> C8) gr2-gr3_slope 0 0 0 0 0 1 -1 0
>> C9) gr2-gr4_intercept 0 1 0 -1 0 0 0 0
>> C10) gr2-gr4_slope 0 0 0 0 0 1 0 -1
>> C11) gr3-gr4_intercept  0 0 1 -1 0 0 0 0
>> C12) gr3-gr4_slope 0 0 0 0 0 0 1 -1
>> C13) gr1+gr2-vs-gr3+gr4.intercept 0.5 0.5 -0.5 -0.5 0 0 0 0
>> C14) gr1+gr2-vs-gr3+gr4.slope 0 0 0 0 0.5 0.5 -0.5 -0.5
>> C15) group.effect.intercept
>> 1 -1 0 0 0 0 0 0
>> 1 0 -1 0 0 0 0 0
>> 1 0 0 -1 0 0 0 0
>> C16) group.effect.slope
>> 0 0 0 0 1 -1 0 0
>> 0 0 0 0 1 0 -1 0
>> 0 0 0 0 1 0 0 -1
>
>> ----Messaggio originale----
>> Da: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
>> Data: 9-ott-2017 22.56
>> A: <freesurfer@nmr.mgh.harvard.edu>
>> Ogg: Re: [Freesurfer] R: Re: R: Re: R: Re: R: Re: Map of covariance
>>
>> I don't know what you are asking
>>
>>
>> On 10/6/17 9:24 AM, std...@virgilio.it wrote:
>>> Thank you very much.
>>> Where I should put 0 0 0 0 .25 .25 .25 .25?
>>> Which are the contrast reported below that I should modify?
>>>
>>> C1) gr1-gr2_intercept 1 -1 0 0 0 0 0 0
>>> C2 )gr1-gr2_slope 0 0 0 0 1 -1 0 0
>>> C3) gr1-gr3_intercept 1 0 -1 0 0 0 0 0
>>> C4) gr1-gr3_slope 0 0 0 0 1 0 -1 0
>>> C5) gr1-gr4_intercept 1 0 0 -1 0 0 0 0
>>> C6) gr1-gr4_slope 0 0 0 0 1 0 0 -1
>>> C7) gr2-gr3_intercept 0 1 -1 0 0 0 0 0
>>> C8) gr2-gr3_slope 0 0 0 0 0 1 -1 0
>>> C9) gr2-gr4_intercept 0 1 0 -1 0 0 0 0
>>> C10) gr2-gr4_slope 0 0 0 0 0 1 0 -1
>>> C11) gr3-gr4_intercept  0 0 1 -1 0 0 0 0
>>> C12) gr3-gr4_slope 0 0 0 0 0 0 1 -1
>>> C13) gr1+gr2-vs-gr3+gr4.intercept 0.5 0.5 -0.5 -0.5 0 0 0 0
>>> C14) gr1+gr2-vs-gr3+gr4.slope 0 0 0 0 0.5 0.5 -0.5 -0.5
>>> C15) group.effect.intercept
>>> 1 -1 0 0 0 0 0 0
>>> 1 0 -1 0 0 0 0 0
>>> 1 0 0 -1 0 0 0 0
>>> C16) group.effect.slope
>>> 0 0 0 0 1 -1 0 0
>>> 0 0 0 0 1 0 -1 0
>>> 0 0 0 0 1 0 0 -1
>>>
>>>
>>>> ----Messaggio originale----
>>>> Da: "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
>>>> Data: 3-ott-2017 16.19
>>>> A: <freesurfer@nmr.mgh.harvard.edu>
>>>> Ogg: Re: [Freesurfer] R: Re: R: Re: R: Re: Map of covariance
>>>>
>>>> probably you want 0 0 0 0 .25 .25 .25 .25
>>>>
>>>>
>>>>
>>>> On 10/3/17 10:10 AM, std...@virgilio.it wrote:
>>>>> Many thank for your response.
>>>>> Claryfing my question on point 3,
>>>>> When I look in group.effect.slope, the map show the group difference
>>> removing
>>>>> the effect of the covariate.
>>>>> Conversely, I would to obtain the map reporting only the effect of
>>> covariate
>>>>> on dependent variable (functional connectivity).
>>>>> Is possible to look on it?
>>>>> Regards
>>>>> Stefano
>>>>>
>>>>>
>>>>>> ----Messaggio originale----
>>>>>> Da: "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
>>>>>> Data: 2-ott-2017 16.58
>>>>>> A: <freesurfer@nmr.mgh.harvard.edu>
>>>>>> Ogg: Re: [Freesurfer] R: Re: R: Re: Map of covariance
>>>>>>
>>>>>>
>>>>>>
>>>>>> On 10/01/2017 05:08 PM, std...@virgilio.it wrote:
>>>>>>> Hi,
>>>>>>> on 4 groups, 1 covariate (4GV1)
>>>>>>>
>>>>>>> I run mri_glmfit using the following .mtx
>>>>>>>
>>>>>>> C1) gr1-gr2_intercept 1 -1 0 0 0 0 0 0
>>>>>>> C2 )gr1-gr2_slope 0 0 0 0 1 -1 0 0
>>>>>>> C3) gr1-gr3_intercept 1 0 -1 0 0 0 0 0
>>>>>>> C4) gr1-gr3_slope 0 0 0 0 1 0 -1 0
>>>>>>> C5) gr1-gr4_intercept 1 0 0 -1 0 0 0 0
>>>>>>> C6) gr1-gr4_slope 0 0 0 0 1 0 -1 0
>>>>>> should be
>>>>>>
>>>>>> 0 0 0 0 1 0 0 -1
>>>>>>
>>>>>>> C7) gr2-gr3_intercept 0 1 -1 0 0 0 0 0
>>>>>>> C8) gr2-gr3_slope 0 0 0 0 0 1 -1 0
>>>>>>> C9) gr2-gr4_intercept 0 1 0 -1 0 0 0 0
>>>>>>> C10) gr2-gr4_slope 0 0 0 0 0 1 0 -1
>>>>>>> C11) gr3-gr4_intercept  0 0 1 -1 0 0 0 0
>>>>>>> C12) gr3-gr4_slope 0 0 0 0 0 0 1 -1
>>>>>>> C13) gr1+gr2-vs-gr3+gr4.intercept 0.5 0.5 -0.5 -0.5 0 0 0 0
>>>>>>> C14) gr1+gr2-vs-gr3+gr4.slope 0 0 0 0 0.5 0.5 -0.5 -0.5
>>>>>>> C15) group.effect.intercept
>>>>>>> 1 -1 0 0 0 0 0 0
>>>>>>> 1 0 -1 0 0 0 0 0
>>>>>>> 1 0 0 -1 0 0 0 0
>>>>>>> C16) group.effect.slope
>>>>>>> 0 0 0 0 1 -1 0 0
>>>>>>> 0 0 0 0 1 0 -1 0
>>>>>>> 0 0 0 0 1 0 0 -1
>>>>>>>
>>>>>>> Please:
>>>>>>> 1) Could you check whether the all .mtx are complete and corrected, in
>>>>>>> particular the gr1+gr2-vs-gr3+gr4.intercept and the gr1+gr2-vs-gr3+gr4.
>>>>> slope?
>>>>>> they look correct, except for the one i noted
>>>>>>> 2) Could you explain the meaning of:
>>>>>>> gr1+gr2-vs-gr3+gr4.slope - does the average slope of grp1 and grp2
> differ
>>>>> from that of grp3 and 4
>>>>>>> gr1+gr2-vs-gr3+gr4.intercept - same
>>>>>>> group.effect.slope - interaction between group and covariate
>>>>>>> group.effect.intercept - is there an effect of group on the inercept
>>>>>>> 3) Which is the contrast identifying the effect of covariate on group
>>>>>>> differences?
>>>>>> not sure what you mean
>>>>>>> Thanks
>>>>>>>
>>>>>>> Best regards
>>>>>>>
>>>>>>>
>>>>>>> Stefano
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>> ----Messaggio originale----
>>>>>>>> Da: "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
>>>>>>>> Data: 5-set-2017 22.59
>>>>>>>> A: <freesurfer@nmr.mgh.harvard.edu>
>>>>>>>> Ogg: Re: [Freesurfer] R: Re: Map of covariance
>>>>>>>>
>>>>>>>> you would need to create a contrast to look for the interaction. If
> you
>>>>>>>> have four gruops and 1 covariate, then it would be
>>>>>>>>
>>>>>>>> 0 0 0 0 1 -1 0 0
>>>>>>>>
>>>>>>>> 0 0 0 0 1 0 -1 0
>>>>>>>>
>>>>>>>> 0 0 0 0 1 0 0 -1
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>> On 09/05/2017 04:32 PM, std...@virgilio.it wrote:
>>>>>>>>> Hi,
>>>>>>>>> e.g., by considering two or more groups, I would like to map the
>>> clusters
>>>>>>>>> reporting the covariance between the functional connectivity or
>>> cortical
>>>>>>>>> thickness (dependent variable) and age, tacking in account the group
>>>>>>>>> differences.
>>>>>>>>> Instead, I'm not interested to map the group differences, taking in
>>>>> account
>>>>>>>>> the nuisance factors.
>>>>>>>>> Thanks,
>>>>>>>>> Stefano
>>>>>>>>>
>>>>>>>>>> ----Messaggio originale----
>>>>>>>>>> Da: "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
>>>>>>>>>> Data: 5-set-2017 18.12
>>>>>>>>>> A: <freesurfer@nmr.mgh.harvard.edu>
>>>>>>>>>> Ogg: Re: [Freesurfer] Map of covariance
>>>>>>>>>>
>>>>>>>>>> I don't understand what you are asking. can you elaborate?
>>>>>>>>>>
>>>>>>>>>>
>>>>>>>>>> On 08/30/2017 12:50 PM, std...@virgilio.it wrote:
>>>>>>>>>>> Hi list,
>>>>>>>>>>> by applying a design e.g. 4GV1 in fsgd I could assess the
> dependence
>>>>>>>>>>> of group differences taking in account the effect of covariate.
>>>>>>>>>>> Anyway, where I should look if I want assess the the map showing
> the
>>>>>>>>>>> clusters in which the dependent variable is associated to
> covariate,
>>>>>>>>>>> tacking in account the group difference? Please could you suggest
> my
>>>>>>>>>>> the path?
>>>>>>>>>>> Thanks
>>>>>>>>>>>
>>>>>>>>>>> Stefano
>>>>>>>>>>>
>>>>>>>>>>>
>>>>>>>>>>> _______________________________________________
>>>>>>>>>>> Freesurfer mailing list
>>>>>>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>>>>> -- 
>>>>>>>>>> Douglas N. Greve, Ph.D.
>>>>>>>>>> MGH-NMR Center
>>>>>>>>>> gr...@nmr.mgh.harvard.edu
>>>>>>>>>> Phone Number: 617-724-2358
>>>>>>>>>> Fax: 617-726-7422
>>>>>>>>>>
>>>>>>>>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>>>>>>>>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>>>>>>>>>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>>>>>>>>> Outgoing: ftp://surfer.nmr.mgh.harvard.
>>> edu/transfer/outgoing/flat/greve/
>>>>>>>>>> _______________________________________________
>>>>>>>>>> Freesurfer mailing list
>>>>>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>>>>>
>>>>>>>>>>
>>>>>>>>>> The information in this e-mail is intended only for the person to
> whom
>>>>> it
>>>>>>> is
>>>>>>>>>> addressed. If you believe this e-mail was sent to you in error and
> the
>>>>> e-
>>>>>>> mail
>>>>>>>>>> contains patient information, please contact the Partners Compliance
>>>>>>> HelpLine
>>>>>>>>> at
>>>>>>>>>> http://www.partners.org/complianceline . If the e-mail was sent to
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>>>>> in
>>>>>>>>> error
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>>>>>>>>> _______________________________________________
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>>>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>>>>
>>>>>>>>>
>>>>>>>> -- 
>>>>>>>> Douglas N. Greve, Ph.D.
>>>>>>>> MGH-NMR Center
>>>>>>>> gr...@nmr.mgh.harvard.edu
>>>>>>>> Phone Number: 617-724-2358
>>>>>>>> Fax: 617-726-7422
>>>>>>>>
>>>>>>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>>>>>>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>>>>>>>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>>>>>>> Outgoing: ftp://surfer.nmr.mgh.harvard.
> edu/transfer/outgoing/flat/greve/
>>>>>>>> _______________________________________________
>>>>>>>> Freesurfer mailing list
>>>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>>>
>>>>>>> _______________________________________________
>>>>>>> Freesurfer mailing list
>>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>>
>>>>>>>
>>>>>> -- 
>>>>>> Douglas N. Greve, Ph.D.
>>>>>> MGH-NMR Center
>>>>>> gr...@nmr.mgh.harvard.edu
>>>>>> Phone Number: 617-724-2358
>>>>>> Fax: 617-726-7422
>>>>>>
>>>>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>>>>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>>>>>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>>>>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>>>>>
>>>>>> _______________________________________________
>>>>>> Freesurfer mailing list
>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>
>>>>> _______________________________________________
>>>>> Freesurfer mailing list
>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>
>>>>>
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>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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