I think you probably should since you don't want whatever you find to only reflect differences in head size

cheers
Bruce
On Sat, 2 Dec 2017, 郑凤莲 wrote:

Hi Bruce,

    I think I get it. I have 27 males and 28 females and 26 males. It isn't 
necessary to corrected by eTIV. Is it right?

Thanks a lot !
Zheng





At 2017-12-02 11:45:10, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>Hi Zheng
>
>For volume, usually including eTIV reduces the variance and increases power >more than you lose for having one additional regressor. Not sure about >gender - how unbalanced is your sample? You might be ok with just eTIV
>Bruce
>
>
>On Sat, 2 Dec 2017, 郑凤莲 >wrote:
>
>> Hi professor,
>> >>    I am using Freesurfer 6.0 and get the volume of subcortical structures. I want to get the relationship between age a
nd
>> volume. I only have one group, is it necessary to take gender and  eTIV as a 
covariate? If it is necessary, Which
>> statistical analysis should be used?
>>    I really appreciate your help. Thanks a lot.
>> >> Sincerely,
>> Zheng
>> >> >> >>



 


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