Thanks Bruce.

I went over some more images with our PI and he was mostly satisfied with the 
pial/white segmentations. The real problem here is that our results look 
correct, except for they seem to be translated vertically by a small amount, 
comparing with what we see on the MRIs. What can we check to make sure 
everything is lining up correctly?

- Eli

On Thu, 2018-01-11 at 08:08 -0500, freesurfer-requ...@nmr.mgh.harvard.edu wrote:

Message: 5
Date: Wed, 10 Jan 2018 20:26:11 +0000
From: "Rockers, Elijah D." 
<edrock...@houstonmethodist.org<mailto:edrock...@houstonmethodist.org>>
Subject: [Freesurfer] reconstruction for very significant atrophy
To: "freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu>" 
<freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu>>
Message-ID: 
<1515615971.3868.3.ca...@houstonmethodist.org<mailto:1515615971.3868.3.ca...@houstonmethodist.org>>
Content-Type: text/plain; charset="utf-8"

Hello,

We have some images that reflect severe atrophy in some subjects, in which gray 
matter is virtually undetectable on the MRI in some regions. However, upon 
checking the segmentations visually, the white/pial surfaces are reflecting a 
significant cortical thickness in these areas.

Is there perhaps any recon-all setting that might extend the white matter area 
out a little more aggressively than it does with the default settings?

Thanks,

- Eli

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------------------------------

Message: 6
Date: Wed, 10 Jan 2018 15:28:25 -0500 (EST)
From: Bruce Fischl 
<fis...@nmr.mgh.harvard.edu<mailto:fis...@nmr.mgh.harvard.edu>>
Subject: Re: [Freesurfer] reconstruction for very significant atrophy
To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu>>
Message-ID:
        
<alpine.lrh.2.20.1801101527330.32...@gate.nmr.mgh.harvard.edu<mailto:alpine.lrh.2.20.1801101527330.32...@gate.nmr.mgh.harvard.edu>>
Content-Type: text/plain; charset=US-ASCII; format=flowed

Hi Eli

it's hard to say without looking at an image. Can you upload a subject and
point us at a spot you think is incorrect? And do you really think the
thickness should be 0 - there is no gray matter left at all? That seems
unlikely....

cheers
Bruce
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