I don't think it is possible to do as a mixed effect. You can do this with the standard GLM by using a per vertex regressor (--pvr thickness.mgh to mri_glmfit)
On 06/27/2018 12:12 PM, Mark Wagshul wrote: > > External Email - Use Caution > > Dear Freesurfer experts, > > We are interested in looking at the moderating effect of grey matter > thickness on a non-imaging outcome measure. Thus, the model would be: > > Outcome measure = Condition + GM thickness + Condition * GM thickness > + covariates. > > where Condition is a categorical variable (1/2, for two conditions of > the non-imaging measures). The Freesurfer GLM usually solves for the > thickness as a function of some contrast, but is really just > determining the voxel-wise statistical significant of a GLM, so should > be doable even with the imaging variable on the RHS. Ideally, we > would like to run this as a linear mixed model with subject as a > random effect, and the condition as a repeated measure. > > Is this possible to do with the current Freesurfer software, and if > so, how would I implement it? > > Thanks for any advice you can provide. > > Mark > > ____________________ > Mark Wagshul, PhD > Associate Professor > Gruss Magnetic Resonance Research Center > Albert Einstein College of Medicine > Bronx, NY 10461 > > Ph: 718-430-4011 > > FAX: 718-430-3399 > > Email: mark.wags...@einstein.yu.edu <mailto:mark.wags...@einstein.yu.edu> > > einstein-logo-rgb > > This email message and any accompanying attachments may contain > privileged information intended only for the named recipient(s). If > you are not the intended recipient(s), you are hereby notified that > the dissemination, distribution, and or copying of this message is > strictly prohibited. If you receive this message in error, or are not > the named recipient(s), please notify the sender at the email address > above, delete this email from your computer, and destroy any copies in > any form immediately. > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
