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Hello,

I am trying to perform a paired analysis for a data set that has subjects'
who belong to either group1 or group2 and have data at time point1 (tp1)
and time point2 (tp2). I am following all the steps on the wiki but I want
to clarify if the contrasts I plan to use for my analyses are appropriate.

For my analyses, I only have two groups and no covariates. I am interested
to know if the decrease in cortical thickness of subjects in group 1 across
tp1 and tp2 is more than the decrease in cortical thickness of subjects in
group 2 across tp1 and tp2. The contrast I think should be used for this
is: 1 -1. Is that correct?

I am also interested to know if the cortical thickness decreased for
subjects regardless of the groups so should I use the contrast: 1 for that?

Best,
Srishti
Social/Clinical Research Specialist
Child Imaging Research and Life Experiences Lab
University of North Carolina at Chapel Hill
email (W): srish...@email.unc.edu
skype: srishti.goel12
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