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It worked as intended. Thank you very much.

On Tue, Oct 8, 2019 at 6:43 PM Greve, Douglas N.,Ph.D. <
[email protected]> wrote:

> In that case, run mris_preproc in the same way but don't include the
> paired-diff. Concatenate the two groups together to give you one file.
> Smooth as you did before. Now with that one file run
> mri_segstats --seg csdbase.sig.ocn.mgh --i youronefile.mgh --avgwf
> subject.hemi.cluster.dat --excludeid 0
>
> The output file subject.hemi.cluster.dat will have a row for each
> subject and hemisphere (the order will be subject.lh, subject.rh,
> nextsubject.lh, nextsubject.rh) and a column for each cluster. The
> values will be the thickness.
>
>
>
> On 10/8/19 12:22 PM, Jose Graterol wrote:
> >
> >         External Email - Use Caution
> >
> > Aha, yes. That is what I want. The original thickness values.
> >
> > Greve, Douglas N.,Ph.D. <[email protected]
> > <mailto:[email protected]>> schrieb am Di., 8. Okt. 2019, 17:36:
> >
> >     That all looks fine, I'm just not sure what problem you want me to
> >     solve. You said that the values in the y.ocn.dat file were all
> >     negative,
> >     it has to be this way because you specified only negative values when
> >     you ran glmfit-sim (and negative values are possible because you have
> >     computed left-right and negated half of your subjects). Do you
> >     want the
> >     original thickness values?
> >
> >     On 10/8/19 11:14 AM, Jose Graterol wrote:
> >     >
> >     >         External Email - Use Caution
> >     >
> >     > I will try to go back a bit, just to be sure I did not make a
> >     mistake.
> >     > I registered both hemispheres of every subject (affected and
> >     > non-affected) with xhemi.
> >     >
> >     > Then for the left-affected subjects I ran:
> >     > mris_preproc --target fsaverage_sym --hemi lh --xhemi --paired-diff
> >     > --srcsurfreg fsaverage_sym.sphere.reg --meas thickness --out
> >     > leftlesionsubjects.lh.lh-rh.thickness.sm00.mgh --s sub-xxx
> >     >
> >     > For the right-affected:
> >     > mris_preproc --target fsaverage_sym --hemi lh --xhemi --paired-diff
> >     > --srcsurfreg fsaverage_sym.sphere.reg --meas thickness --out
> >     > rightlesionsubjects.lh.lh-rh.thickness.sm00.mgh --s sub-xxx
> >     >
> >     > Then I changed the sign of the right-affected subjects:
> >     > fscalc rightlesionsubjects.lh.lh-rh.thickness.sm00.mgh mul -1 -o
> >     > rightlesionsubjects.lh.rh-lh.thickness.sm00.mgh
> >     >
> >     > Then I concatenated them:
> >     >
> >     > mri_concat leftlesionsubjects.lh.lh-rh.thickness.sm00.mgh
> >     > rightlesionsubjects.lh.rh-lh.thickness.sm00.mgh --o
> >     > allsubjects.lh.lesion-healthy.thickness.sm00.mgh
> >     >
> >     > Then I smoothed the file:
> >     > mris_fwhm --s fsaverage_sym --hemi lh --cortex --smooth-only
> >     --fwhm 10
> >     > --i allsubjects.lh.lesion-healthy.thickness.sm00.mgh --o
> >     > allsubjects.lh.lesion-healthy.thickness.sm10.mgh
> >     >
> >     > Then glmfit:
> >     > mri_glmfit --y allsubjects.lh.lesion-healthy.thickness.sm10.mgh
> >     > --glmdir glmdir.allsubjects.lh.lesion-healthy.thickness.sm10 --osgm
> >     > --surf fsaverage_sym lh
> >     >
> >     > and finally the correction for multiple comparisons:
> >     >
> >     > mri_glmfit-sim --y allsubjects.lh.lesion-healthy.thickness.sm10.mgh
> >     >  --glmdir glmdir.allsubjects.lh.lesion-healthy.thickness.sm10
> >     > --cwpvalthresh 0.05 --cache 4 neg
> >     >
> >     >
> >     > Hopefully this helps.
> >     >
> >     >
> >     >
> >     >
> >     > On Tue, Oct 8, 2019 at 4:45 PM Greve, Douglas N.,Ph.D.
> >     > <[email protected] <mailto:[email protected]>
> >     <mailto:[email protected] <mailto:[email protected]>>>
> >     wrote:
> >     >
> >     >     The input has both positives and negatives, so is is not
> >     >     surprising that the y.ocn.dat also has positive and
> >     negative. Not
> >     >     sure what is going wrong here ...
> >     >
> >     >     On 10/7/2019 5:48 PM, Jose Graterol wrote:
> >     >>
> >     >>             External Email - Use Caution
> >     >>
> >     >>     Ok, I uploaded it with the name
> >     "glmdir.jg.allsubjects.tar.gz". I
> >     >>     had to log in as anonymous and not with my email, otherwise it
> >     >>     would throw an error (503 Login with USER first. Login
> >     failed.).
> >     >>     The mgh file is inside the gz file too. Thanks again for your
> >     >>     time and help.
> >     >>
> >     >>     On Mon, Oct 7, 2019 at 7:06 PM Greve, Douglas N.,Ph.D.
> >     >>     <[email protected] <mailto:[email protected]>
> >     <mailto:[email protected] <mailto:[email protected]>>>
> >     wrote:
> >     >>
> >     >>         ok, I still don't know what is going on. Can you upload
> the
> >     >>         glmdir and the input to mri_glmfit (ie, the argument of
> the
> >     >>         --y flag). You can upload it using these instructions:
> >     >>
> >     >>         From the linux command line,
> >     >>         Create the file you want to upload, eg,
> >     >>         cd $SUBJECTS_DIR
> >     >>         tar cvfz subject.tar.gz ./subject
> >     >>         Now log  into our anonymous FTP site:
> >     >>         ftp surfer.nmr.mgh.harvard.edu
> >     <http://surfer.nmr.mgh.harvard.edu>
> >     >>         <http://surfer.nmr.mgh.harvard.edu>
> >     >>         It will ask you for a user name: use your email address
> >     >>         It will ask you for a password: use "anonymous" (no
> quotes)
> >     >>         cd transfer/incoming
> >     >>         put subject.tar.gz
> >     >>
> >     >>         Send an email that the file has been and the name of
> >     the file.
> >     >>
> >     >>         On 10/7/2019 11:53 AM, Jose Graterol wrote:
> >     >>>
> >     >>>                 External Email - Use Caution
> >     >>>
> >     >>>         Hi Douglas,
> >     >>>
> >     >>>         thanks for you answer. I have attached the file to the
> >     email.
> >     >>>
> >     >>>         On Mon, Oct 7, 2019 at 5:24 PM Greve, Douglas N.,Ph.D.
> >     >>>         <[email protected]
> >     <mailto:[email protected]> <mailto:[email protected]
> >     <mailto:[email protected]>>> wrote:
> >     >>>
> >     >>>             Let's backup a moment. Can you send the y.ocn.dat
> file
> >     >>>             that has problematic values?
> >     >>>
> >     >>>             On 10/4/2019 4:58 AM, Jose Graterol wrote:
> >     >>>>
> >     >>>>                     External Email - Use Caution
> >     >>>>
> >     >>>>             Dear Freesurfer Experts,
> >     >>>>
> >     >>>>             I would appreciate your help. I will explain
> >     first what
> >     >>>>             I have done and where my problem is.
> >     >>>>
> >     >>>>             I want to measure the cortical thickness in stroke
> >     >>>>             patients. Therefore I followed Douglas' instructions
> >     >>>>             provided in this link
> >     >>>>
> >      <
> https://www.mail-archive.com/[email protected]&q=subject:%22%5C%5BFreesurfer%5C%5D+flipping+surface+data%22&o=newest&f=1
> >to
> >     >>>>             join both affected hemispheres (left or right,
> >     >>>>             depending on the patient) and to analyze them
> >     with xhemi.
> >     >>>>
> >     >>>>             After mri_glmfit and mri_glmfit-sim (--cwpvalthresh
> >     >>>>             0,05 --cache 4 abs/neg) have run I obtained 2
> >     >>>>             significant clusters. One in the precentral area,
> >     which
> >     >>>>             I am interested in. When I check the
> >     *abs/neg.y.ocn.dat
> >     >>>>             file the values are all -0.XXXX. If I understood it
> >     >>>>             correctly, those should be cortical thickness
> >     values in
> >     >>>>             mm, making those values implausible. For that
> >     reason I
> >     >>>>             made a label of that cluster using the autofill
> >     option
> >     >>>>             from tksurfer. The idea was to obtain the mean
> >     cortical
> >     >>>>             thickness using mris_anatomical_stats after
> >     mapping the
> >     >>>>             label to the subjects.
> >     >>>>
> >     >>>>             Now my questions, what would be the best method
> >     to map
> >     >>>>             the label created from the fsaverage_sym space to
> the
> >     >>>>             subject space? Or just simply, is this the right
> >     way to
> >     >>>>             do this? or should I check why I am obtaining those
> >     >>>>             values in the *y.ocn.dat file?
> >     >>>>
> >     >>>>             Thanks in advance.
> >     >>>>
> >     >>>>             Kind Regards
> >     >>>>
> >     >>>>             José Graterol
> >     >>>>
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