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Hi Doug,

Thank you. Makes sense. Is there any way to visualize significance overlays for 
the subcortical volumes?

I've also moved on to the correction for multiple comparisons in my subcortical 
volumes, using:

mri_glmfit-sim -- glmdir roi.binarygroup.glmdir --perm 1000 1.3 abs --cwp 0.05 
--2spaces --bg 1

This did not create any new files in the Contrast subdirectories, but the log 
file does say that it was run and finished. Can I find a table with corrected 
p-values anywhere? Or would it make more sense to move the aseg_table into a 
different stats package and calculate my GLM there, correcting for multiple 
comparisons post-hoc (manually)?

Thank you so much
Julia

NIHR Maudsley Biomedical Research Centre PhD Student
Forensic & Neurodevelopmental Sciences
Institute of Psychiatry, Psychology & Neuroscience
King's College London
16 De Crespigny Park, Camberwell
London, SE5 8AB

From: freesurfer-boun...@nmr.mgh.harvard.edu 
<freesurfer-boun...@nmr.mgh.harvard.edu> On Behalf Of Douglas N. Greve
Sent: 15 April 2021 15:14
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] glmfit with aseg table: view surface overlay

The input is a table, so the output is a table (the sig.mgh file will just have 
the number of values that are in the table; this is not a "volume" you can look 
at in FV). Look in the sig.table.dat file for the sigs.
On 4/13/2021 8:41 AM, Griem, Julia wrote:

        External Email - Use Caution

        External Email - Use Caution
Dear Freesurfer team,

I am comparing subcortical volumes (aseg table) in 2 groups with no other 
variables. Based on the GLM lecture slides from the course I attended, I ran 
the following glmfit command:
mri_glmfit
--table aseg_table.txt
--fsgd FSGD/DemographicsSubcortBinaryGroup.fsgd
--C Contrasts/HC-ASPD.mtx
--C Contrasts/ASPD-HC.mtx
--glmdir roi.binarygroup.glmdir

It created all the correct output and subdirectories.

I then used
freeview -f $SUBJECTS_DIR/fsaverage/surf/lh.inflated:overlay=ASPD-HC/sig.mgh

but an error saying "failed to load surface overlay" comes up and the terminal 
error message is "number of vertices in overlay data does not match with 
surface". I assume this is because I am trying to load a 'whole-brain' sig.mgh 
onto a lh surface? Do I have to change the glmfit command to specify 
hemispheres, and if so, how do I do that since I do not want to look at 
cortical but subcortical data? Or alternatively, can I load both hemispheres 
into freeview so the overlay sig.mgh fits?

Thank you so much,
Julia



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