External Email - Use Caution Hi FS team,
I am running a morphometry study on a public dataset with most, but not all, subjects having a T1 and T2 (about 75% have both, remaining only have T1). To get the best surfaces possible, I have been including the T2 in recon-all process when able to. However, this means subjects with only a T1 have underwent a different processing workflow. ICV is an important predictor in my study, and I was wondering if the presence of the T2 image in recon-all should impact the ICV estimates? As I see it, I have the following options: 1) T2 is a factor, so I use only include T1 in recon-all so all subjects have the same pipeline 2) T2 is a factor, so I harmonize the data as I would with data from different sites/scanners 3) T2 is a factor, so I only analyze subjects with T1 + T2 4) T2 is not a factor, just use all subjects with no special considerations I am also running vertex-wise surface based morphometry, where I imagine pial refinements could be more impactful. I suppose in that case, I should harmonize the morphometry data, but was curious if you think something like that is necessary. Thank you, Steven Meisler _______________________________________________ Freesurfer mailing list [email protected] https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at https://www.massgeneralbrigham.org/complianceline <https://www.massgeneralbrigham.org/complianceline> . Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
