External Email - Use Caution what is roi_in_MNI152.mgz? If that is an binary ROI mask, then that will certainly fail. Try something like mri_coreg --mov orig.mgz --dof 12 --reg reg.mni152.lta --targ mni152-template.nii.gz where mni152 template is an intensity volume in voxel-for-voxel registration with your roi volume, then mri_vol2vol --interp nearest --mov orig.mgz --targ roi_in_MNI152.mgz  --reg reg.mni152.lta --inv

On 5/18/2023 5:33 PM, Carlos Alcocer wrote:

        External Email - Use Caution

Hi,

I am trying to transform a volumetric ROI from MNI152 space to native space. I am doing this in 2 steps. First (1) I am creating a registration file using bb register to create a registration file and then (2) I am using mri_vol2vol to transform volume onto my subject using the registration file I created in step 1.

1. bbregister --s subjid --mov roi_in_MNI152.mgz --t1 --reg register.dat

2. mri_vol2vol --targ subjid/mri/T1.mgz --mov roi_in_MNI152.mgz --reg register.dat --o roi_in_native.mgz

However, the transformed volume is not anatomically positioned where it is supposed to be. Is there an error in my method?

Thank you,

Carlos

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