External Email - Use Caution Dear FreeSurfer Team,
I’m currently working on a project involving cortical morphology and am particularly interested in calculating Intrinsic Cortical Curvature (ICC) using FreeSurfer. I came across a recent publication ( https://secure-web.cisco.com/1oL8IZPRfQ5o5UDqVHfF8rU4SLPTHeXEdS4OHOftgKkxaXnXs_JcjgvX9Pe6OjBAkg-u6fxy2Cx-D41wHlEOMEUS_Tk4d7v7Qx3Likv_shYeRtBnydcyfIwu-HBDJKzLVej16EUEX-HNd8WGxTf7Ghvp8It6AivG6yuekw2Fms7MQqM2usIj69bSUOCgHXEJVNndJssFPN8-cnhlMpo8F3l1h9DmbUW45d2fUw_JIGOzVK4lBhAakU7epXVGW1WTQ80Aykb2L7XDlPgosOWOufDrB0xiUu0Tc0OmbMxmp5guJBLGRXwomIYU_9p_795vNmXJLXjWb0vLGetc7x5nWPw/https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F38761434%2F) that utilized ICC in their statistical analysis. I’d like to clarify a couple of points regarding how ICC is derived within the FreeSurfer framework: 1. Is Gaussian curvature as computed by FreeSurfer considered equivalent to ICC? 2. If not, are there additional steps or specific tools required to compute ICC beyond the standard curvature outputs (e.g., via mris_curvature or mris_curvature_stats)? Any guidance or documentation you could share would be greatly appreciated. I’m aiming to ensure methodological consistency with published work and would be grateful for your insights. Thank you for your time and support. With regards, Vittal
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