Sorry.  Misspoke.  Don't really make a distinction between human nature and the 
human condition.  Each is a creation of the other.  they are dialectically 
intertwined.... or whatever.  So, you cant disagree with me on that point any 
more.   

So, let's take this occasion to transition to a different topic ... 
development.  I have been Sean Carroll's Endless Forms most Beautiful.  It is 
the forth book I have read written by a brilliant author designed to explain 
modern "EvoDevo" to the great unwashed.  And I have to say, I still don't quite 
"get it"  But I think I am beginning to understand why ... the metaphors they 
use are bad.  Nobody has come up with a good metaphor to come up with how we 
now know development to work.  How do we get pluris e uno?

The stunning discovery of the last 25 years is how widely and in what detail 
sequences of genes are similar among animals of widely different form.  The 
metaphor they use is of a genetic tool kit.  Even tho organisms have many 
different genes, they all share an essential toolkit.  Carroll actually depicts 
a little toolbox with cubbies  in for the "tools".  The DNA sequences in this 
basic, shared tool kit are often similar down to the last base.  So even though 
planaria, bees, octopi, and humans have wildly different eyes, the making of 
eyes in all of these species is dependent upon a shared sequence of genes that 
generate a shared bunch of proteins.  

But the tool kit metaphor leads Carroll into a ghastly anthropomorphic trap.  
Once we have tools, we need a craftsman, right?  Well, in Carroll's hand, the 
tools themselves become the craftsmen.   So, in caption of a photography 
showing the embryonic development of a frog's "hand" we get the following:   
"The BMP4 tool kit a gene marks the tissue between the digits that will die."  
In general, reading the text, one is seduced into a vision of the genes or the 
proteins crawling over the embryo, measuring it out for this and that, and 
leaving stakes in the ground so that the different contractors that are coming 
along will know what to put where.  

Now, don't get me wrong.  I think Carroll's book is stupendous, and I would 
urge you all to drop what you are doing and order it on Amazon today.  Buy this 
"toolkit" thing  has to be wrong.  What is really going on is that fundamental 
physical asymmetries in the ovum are serving as cues that excite portions of 
embryo  to produce one or more of these "tookkit" proteins, which then defuse 
ac cross the embryo.   Then the concentration gradients of these proteins, in 
turn, serve as the cues for the production of proteins that further organize 
the portions of the embryo for further functions.  

So, assuming that I have this correctly, what would be  GOOD metaphor to 
encapsulate this process?  Remember, we have stipulated here repeatedly that 
all metaphors are faulted and that a GOOD metaphor is one whose faults do not 
encourage defunct notions of what is going on.  So, for instance, in matters of 
development, a GOOD metaphor should scrupulously avoid any implication of 
intelligence in its description of what these "organizing" proteins are doing.  

Does any one have a better metaphor?

If any of you are wondering why I am so verbose and wondering, further, when it 
will stop, try sending some decent weather to Massachusetts.  
Eleventh straight day of rain.  

N



Nicholas S. Thompson
Emeritus Professor of Psychology and Ethology, 
Clark University ([email protected])
http://home.earthlink.net/~nickthompson/naturaldesigns/




----- Original Message ----- 
From: peggy miller 
To: [email protected]
Sent: 6/21/2009 11:42:22 AM 
Subject: [FRIAM] vol 72, issue 25 response


I only wish to say that I disagree with the statement that "ethical behavior is 
built on human nature". It is the "human nature" part that I take issue with. I 
believe each person's sense of ethics comes from a combination of 
education/experiences, social network, physiological chemistry of that person, 
IQ, and genetic makeup. That combination causes a person to form a construct of 
ethics they rely on to defend their behavior. The only other part that throws a 
crux into their formula is the level of spiritual connection they have to the 
greater universe, and I am not yet unconvinced that that particular level of 
connection may also be a genetic thing.

thanks for listening.
Have a good day!

Peggy Miller
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