Marcus -
I believe that Andrew Niccol DID imagine something like that: I wish I had a pithy preamble for this dystopian BioPunk reference, but perhaps it speaks for itself? https://en.wikipedia.org/wiki/Gattaca - Steve > Steve writes: > > < The whole world is responding to what is *roughly* the same virus > with *roughly* what is the same human phenotype/metabolism in a myriad > of *roughly* the same modes of human organization. > > > There are hundreds of common HLA alleles across humans. In a diverse > country like the US, with hundreds of thousands of positive cases and > tens of thousands of deaths the hundreds of alleles would be well > sampled. Too bad our medical surveillance is so bad, and made worse > by the moron. Imagine if everyone had full genome sequencing and > every viral sample was deep sequenced. > > Marcus > ------------------------------------------------------------------------ > *From:* Friam <friam-boun...@redfish.com> on behalf of Steven A Smith > <sasm...@swcp.com> > *Sent:* Sunday, April 19, 2020 10:11 AM > *To:* friam@redfish.com <friam@redfish.com> > *Subject:* Re: [FRIAM] Judea Pearl: Book of Why > > >> One way to address the N/A issue is to repeatedly perturb the real-world >> system so as to elicit those correlations. When that is practical.. > > We are, in a time of real-world system perturbation, right now. The > whole world is responding to what is *roughly* the same virus with > *roughly* what is the same human phenotype/metabolism in a myriad of > *roughly* the same modes of human organization. This IS a testbed of > human (-system?) response to a widespread, somewhat invisible > threat. From Wuhan to Singapore to Italy to Iran to Sweden to > Germany to NYC to WA State to the Navajo Nation to Florida's beaches, > this IS a huge coupled systems dynamics/agent-model executed in > real-time by real-people with real casualties and real consequences. > > We are, to varying degrees (collectively) recording the results of > these "experiments" and if we are lucky (or smart, or both) we will do > some post-game analysis intended to understand more-better how best to > (self-)organize around a (nearly) existential world-scale threat. > And to the extent this is a game that will never end, we have to begin > the analysis while we cope with it's consequences. Feels a bit like > the models pof Physics Interreality. > > https://journals.aps.org/pre/abstract/10.1103/PhysRevE.75.057201 > <https://journals.aps.org/pre/abstract/10.1103/PhysRevE.75.057201> > > Hanging too aggressive of a model on this (or collecting the data > against too premature of a model) will reduce the utility of such data > gathering and analysis. Whatever the dual of overfitting a model > is? Overmodeling? Premature Modeling? > > What I'm looking (askance) to(ward) Pearl for is a better way of > rapidly constructing, maintaining, revising as generic of a model as > possible in response to "this moment". Four months ago we should > have been interested in models of how one limits a virus such as > COVID19 getting a foothold in this country. One month ago we should > have been interested in how one limits COVID19 (with new understanding > of it's virility, it's fatality, it's symptoms, it's mode of spread) > once it HAS a foothold, now we are faced with trying to understand > how to cope with it once it is pervasive in our population whilst > continuing/returning to "business as usual" and in another thread, I'm > encouraging that we "try to plan/consider/think-about" what we want to > do with this somewhat "blank slate" (our ass?) we are having handed > to us. > > And how to think about this without premature modeling... what I think > I was railing (whining/pushing-back) about with Dave on the Bellamyist > thread earlier this morning. > > - Steve > >>> On Apr 19, 2020, at 8:33 AM, uǝlƃ ☣ <geprope...@gmail.com> >>> <mailto:geprope...@gmail.com> wrote: >>> >>> Well, the argument I often end up making is that you can do a kind of face >>> validation with the fake data. Show it to someone who's used to dealing >>> with that sort of data and if the fake data looks a lot like the data they >>> normally deal with, then maybe more data-taking isn't necessary. If it >>> looks fake to the "expert", then more data-taking is definitely needed. >>> >>>> On 4/19/20 8:29 AM, Marcus Daniels wrote: >>>> I have a hard time with this as a way to extend data. If it is >>>> high-dimensional it will be under-sampled. Seems better to me to measure >>>> or simulate more so that the joint distribution can be realistic. And if >>>> you can do that there is no reason to infer the joint distribution because >>>> you *have* it. >>>> >>>>>> On Apr 19, 2020, at 8:18 AM, Frank Wimberly <wimber...@gmail.com> >>>>>> <mailto:wimber...@gmail.com> wrote: >>>>> >>>>> Going back and forth: If you infer the causal graph from observational >>>>> data you can use that graph to simulate data with the same joint >>>>> distribution as the original data. >>> -- >>> ☣ uǝlƃ >>> >>> .-. .- -. -.. --- -- -..-. -.. --- - ... -..-. .- -. -.. -..-. -.. .- ... >>> .... . ... >>> FRIAM Applied Complexity Group listserv >>> Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam >>> unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com >>> archives: http://friam.471366.n2.nabble.com/ >>> FRIAM-COMIC http://friam-comic.blogspot.com/ >> .-. .- -. -.. --- -- -..-. -.. --- - ... -..-. .- -. -.. -..-. -.. .- ... >> .... . ... >> FRIAM Applied Complexity Group listserv >> Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam >> unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com >> archives: http://friam.471366.n2.nabble.com/ >> FRIAM-COMIC http://friam-comic.blogspot.com/ >> > > .-. .- -. -.. --- -- -..-. -.. --- - ... -..-. .- -. -.. -..-. -.. .- ... > .... . ... > FRIAM Applied Complexity Group listserv > Zoom Fridays 9:30a-12p Mtn GMT-6 bit.ly/virtualfriam > unsubscribe http://redfish.com/mailman/listinfo/friam_redfish.com > archives: http://friam.471366.n2.nabble.com/ > FRIAM-COMIC http://friam-comic.blogspot.com/
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