My two cents---

$5K won't buy everything you need, but it will get you started.  I think at
least a 4-core machine with 16GB of RAM should be sufficient for most jobs.
 If you know you need more, get more RAM.

Galaxy is a hog on disk space, so try to maximize disk space.  I would set
up 2 small disks (or partitions), say 20G, as RAID1 for the OS, and the
remaining disks, at least 1-2TB, for Galaxy data as RAID0.

I think that configuration will quickly eat your $5K, but will give you
something to work with. If you still have money to spare, increase CPUs,
RAM, and disks where you can.

Oh - One power supply, 1 NIC card, etc, no redundancy...save some money...

On Wed, May 2, 2012 at 4:01 PM, Stephen Turner <vustep...@gmail.com> wrote:

> The tl;dr short story - I've come across about $5,000 I can use to
> build a machine, and this money has to be spent by Friday. I'd like
> some help spec'ing out a machine that can be used as a small-scale
> production Galaxy server for internal use by a handful of folks.
>
> Would anyone be willing to talk with me tomorrow morning, Thursday May
> 3, and tell me about your experience setting up a Galaxy installation
> on a scale like this? With about $5k to spend, what kind of hardware
> should I prioritize? I'd also like to get a sense of how much admin
> time is required to keep things running smoothly, updated, backed up,
> etc.
>
> I've had a difficult time getting ITS to help me get Galaxy running on
> the university's cluster. This will hopefully be a proof of principal
> that people here want this - hopefully I can get enough people here
> using this small-scale installation that the university ITS realizes
> the demand and has more motivation to get things working on the
> cluster.
>
> Many thanks,
>
> Stephen
>
> -----------------------------------------
> Stephen D. Turner, Ph.D.
> Bioinformatics Core Director
> University of Virginia School of Medicine
> bioinformatics.virginia.edu
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