Hi,
I was using the Genome Browser to examine the structure of the chicken
G6PC gene:
http://genome.ucsc.edu/cgi-bin/hgTracks?position=chr27:4722380-4724914&hgsid=161842089&xenoRefGene=pack&hgFind.matches=NM_001005682,
This browser window indicates the presence of a 'Gap Location'. I presume this
is a region of the chicken genome for which the sequence is unavailable? Is
that correct? This gap region should contain the third exon of the gene,
assuming the structure is the same as that in other species. But strangely the
chicken ests that are shown in the browser do not encode proteins with a
similar ORF as in other species so the alternate possibility is that the G6PC
gene is a pseudogene in chickens, which seems unlikely. More likely the gene
structure is incomplete and a full length chicken cDNA for G6PC remains to be
cloned.
I'd appreciate your thoughts on this.
Regards, Richard O'Brien
Professor
Room 8415 MRB IV
Dept. Molecular Physiology & Biophysics
Vanderbilt University Medical School
Nashville
TN 37232
Tel 615-936-1503
Fax 615-322-7236
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