Hi Richard, It sounds like you are doing a good job of using the Browser resources to interpret and investigate the data. However, we cannot comment about the final interpretation. This is a scientific judgment call we leave for you to decide upon.
Very sorry for any inconvenience this may cause, Jennifer --------------------------------- Jennifer Jackson UCSC Genome Informatics Group http://genome.ucsc.edu/ On 6/7/10 12:13 PM, O'Brien, Richard wrote: > Hi, > > I was using the Genome Browser to examine the structure of the chicken > G6PC gene: > > http://genome.ucsc.edu/cgi-bin/hgTracks?position=chr27:4722380-4724914&hgsid=161842089&xenoRefGene=pack&hgFind.matches=NM_001005682, > > This browser window indicates the presence of a 'Gap Location'. I presume > this is a region of the chicken genome for which the sequence is unavailable? > Is that correct? This gap region should contain the third exon of the gene, > assuming the structure is the same as that in other species. But strangely > the chicken ests that are shown in the browser do not encode proteins with a > similar ORF as in other species so the alternate possibility is that the G6PC > gene is a pseudogene in chickens, which seems unlikely. More likely the gene > structure is incomplete and a full length chicken cDNA for G6PC remains to be > cloned. > > I'd appreciate your thoughts on this. > > Regards, Richard O'Brien > > Professor > Room 8415 MRB IV > Dept. Molecular Physiology& Biophysics > Vanderbilt University Medical School > Nashville > TN 37232 > Tel 615-936-1503 > Fax 615-322-7236 > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
