Peng,

On Tuesday 15 June 2010 05:15:54 pm Peng Yu wrote:
> I just realized that this is an option. But would this waste the
> memory as each process has to load its own genome?

You can set up Blat server for this, see Blat documentation for details. 
Server loads and indexes a sequence in memory that can be used for searching 
by Blast clients over the network. There are some limitations and tradeoffs 
with this configuration so you will need to benchmark your code to find out 
if it will provide enough benefits in your specific case.

Best,
Ivan


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