I had a question about the ENCODE Open Chromatin track, or FAIRE-seq, on the UCSC Genome Browser. It is very obvious where there are peaks or apparent regions of open chromatin, and even where the signal flatlines and there is no signal. But i have noticed there are regions where there is a pink line that falls below the blue flatline, almost like these are regions of "negative" signal. This is sequence data so there should only be two outcomes, either there is sequence or there isnt. So i was wondering what is this pink line?? Ill attach an image of an example i found from FAIREseq performed on K562 cells. The "negative" signal i am talking about is just upstream of the RBP4 gene at chromosome location ~95351500.
Thanks for your feedback, -Derek -- Derek Thibault Technical Research Assistant II Brigham and Women's Hospital Channing Laboratory 221 Longwood Ave. EBRC 320 Boston, MA 02115 phn: 617-732-6061
_______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
