Good Morning Matt:

Are you perhaps observing the 'off-by-1' coordinate FAQ:
http://genome.ucsc.edu/FAQ/FAQtracks#tracks1
http://genomewiki.ucsc.edu/index.php/Coordinate_Transforms

--Hiram

Matthew Schu wrote:
> Hello,
> I created a local Blat server according to the instructions given in the FAQ
> section of your site.  When comparing the results of my query, which were
> returned in psl format, to the results that the online Blat server would
> return I noticed that the two returned different values for the qStart
> positions, yet the qEnd positions were identical.  The local server I set up
> seems to give the position of the first base pair match of the query
> sequence on the genome, however the online Blat server returns the position
> of the base before the first match of the query sequence and the genome.
>  Can anyone tell me why there is a difference and why the online Blat server
> returns the position of the base that is exactly one before the first
> matching base?
> 
> 
> Thank you,
> 
> Matt Schu
> Bioinformatics Grad. Student
> Boston University
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