Hello

I have been using the standalone Blat extensively over the last few  
months using the following command :

blat -stepSize=5 -minScore=0 -minIdentity=0 database.2bit query.fa  
output.psl

which replicates the web-based version of the same as specified on the  
website (http://genome.ucsc.edu/FAQ/FAQblat).


However, I have run into an issue where there is a significant  
difference in the results. For example,

On using the web-based Blat based on the following :

Genome          : Mouse
Assembly        : July 2007
Query Type      : DNA
Sequence        :  
ATTTGTGTGTGTGTGTGTGTTTTTTTTTTTGTTGTTGTTGTTGTTGTTGTTTTGAGACAGGGTTT

The result obtained is
QUERY           SCORE           START           END     QSIZE   IDENTITY        
CHRO    STRAND  START           END             SPAN
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YourSeq           65                          1                    65           
     65             
100.0%               16         +               62887839        62887903        
    65


However, on using the standalone blast, the same sequence yields no  
results.

Kindly, let me know where the problem lies?

Thank you

Amol Carl Shetty
Department of Human Genetics
Emory University
Atlanta, Georgia
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