Hi folks,

I've two general questions. The first is simply a software question. I see from 
the FAQ that y'all generally use both Repeat Masker and TRF to deal with 
repeats, and that repeats are soft-masked. I know how to soft-mask using Repeat 
Masker, but how does one do this on TRF?

Second, I've seen at least one paper 
(http://www.biomedcentral.com/1471-2105/11/80) that strongly suggests that 
repeats should be hard masked. Has this (relatively recent) paper changed your 
thoughts on hard-masking?

Many thanks,

David Garfield
Duke University
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