Hi, Fahim

Here is the command we used to make our rat ooc.

blat rn5.2bit /dev/null /dev/null -tileSize=11 -makeOoc=rn5.11.ooc 
-repMatch=1100

Then, after that you would include this additional blat option:
  -ooc=rn5.11.ooc

It's definitely worth a try.

-Galt

11/30/2010 7:26 AM, Mohammad Fahim:
> Hi
> I am using standalone BLAT for querying est sequences againt human,
> mouse and rat genome.
>
> I am using the following command:
>
> './blatDir/blat -noHead  databaseFiles queryFile tmpPslFile'
>
> here the database and query files are in FASTA format.
>
> I blat for rat est squences (total est sequence for rat is around a
> million) but it is taking time in days. I am intimidated by the toughts
> when I will start doing it for human and mouse.
>
> Can I do something to tune the parameters so that  it becomes even more
> fast(I am becoming more greedy).
>
> In one of the archives it is recommended to use ooC file but since BLAT
> internally create it, do I really need to do that?
>
> Thanks and regards
> Fahim
> Grad Student
> University of Louisville
> KY-USA
>
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> https://lists.soe.ucsc.edu/mailman/listinfo/genome

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