Good Morning Anne:

The 46-way alignment is a 'reference based' based multiple alignment.
The raw data for the alignment are the pair-wise alignments of each
species to the human genome.  The human genome is the reference genome.

You can find the details of the alignment methods in the description
page for the track:

http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=cons46way

--Hiram

Anne Nitsche wrote:
> 
> To whom it may concern,
> 
> 
> I am writing to ask if the raw data of the 46way multiz alignment (human 
> genome as reference) are still anywhere in your database. I need this 
> alignment with *all blocks, irrespective of any reference genome*. Is it 
> possible to get a link for this data?
> 
> 
> Yours sincerely,
> Anne Nitsche
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