On Feb 2, 2011, at 1:00 PM, Mary Goldman <[email protected]> wrote:

> You could calculate the dn/ds ratios yourself using our CDS FASTA
> alignments for both the amino acids and nucleotides for all FlyBase
> genes
> (http://hgdownload.cse.ucsc.edu/goldenPath/dm3/multiz15way/ 
> alignments/).
> It is possible that Ensembl may also have a way to calculate this:
> https://lists.soe.ucsc.edu/pipermail/genome/2004-January/ 
> 003853.html. If
> you have any questions about their website, please contact them at
> http://www.ensembl.org/Help/Contact.
>
> I hope this information is helpful. Please feel free to contact the  
> mail
> list again if you require further assistance.

Ensembl doesn't seem to have dn and ds for flies as they do for  
mammalian species, but the downloadable alignments from UCSC should  
make it easy enough to calculate.  This is very helpful, thank you!

Daniel Dvorkin
Computational Bioscience Program
University of Colorado Denver

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