Hello,

I am emailing to let you know that the Saccharomyces Genome Database (SGD) has 
just released a whole genome sequence update for the Saccharomyces cerevisiae 
reference sequence. We anticipate that this release will serve as a stable 
reference for the foreseeable future and hope that updates to this sequence 
will be exceedingly rare.

Because UCSC is such a popular and useful resource, we would very much 
encourage you to update your S. cerevisiae sequence accordingly. The new 
sequences and annotation are available on our download site:
http://downloads.yeastgenome.org/genome_release/r64/

All 16 S. cerevisiae chromosomes are changed as part of this update, but the 
mitochondrial genome sequence remains the same. As a consequence of these 
changes, 252 individual annotated features are altered (please see below). No 
features were added or deleted. This summary is relative to the last version at 
SGD (01-05-2010); there would be a few additional changes relative to the 
latest version currently available at UCSC (sacCer2, June 2008).

We would be happy to assist you in this process in any way. Please don't 
hesitate to ask if you need any more information or data. If I should be 
talking to someone else in your group about this update, please let me know.

Regards,

-Dianna



The vast majority of annotated features remain unchanged at the nucleotide 
level. The following is a list of the changed features, broken down by feature 
type (#changed/#total feature type). 
13/337 ARSes 
1/383 long terminal repeat 
1/50 retrotransposon 
2/89 transposable element genes (and corresponding exons and/or introns) 
5/32 telomeres (changes in: 1 X element combinatorial repeat, 2 X element core 
sequences, and 2 Y' elements) 
2/15 ncRNAs (and corresponding noncoding exons) 
2/299 tRNAs (and corresponding noncoding exons) 
1/24 5’ UTR introns 
225/6607 protein coding ORFs (and corresponding exons and/or introns) 
-------------------------- 
252/8093 changed features 



****************************************************************
 Dianna Fisk, Ph.D., Database Curator
 Saccharomyces Genome Database
 Stanford University Medical Center
 Department of Genetics
 1501 California Ave, Rm 2C412B
 Palo Alto, CA  94304-5577, USA
 phone: (650) 725-8956
 email:  [email protected]
 http://www.yeastgenome.org/index.html
*****************************************************************









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