To whom it may concern, Currently, we perform an exom sequencing on samples from patients and tried to identify the mutations that caused a genetic disorder. I just received the exom sequencing data with about 700 candidate variants. The only information of these variants are chromosome and physical location. I was wondering if there were some ways that I could import the list of these variants (chromosome and location) into UCSC browser and identified the genes that variants were located and pull out the sequences flanking the variants. Is there any esay way to tell if a variant cause synonymous, nonsynonymous, or nonsense alterations?
Thanks. Dongchuan Guo, PhD Assistant Professor Department of Internal Medicine The University of Texas Medical School at Houston Tel: 713-500-6849 _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
