Hi: I am interested in finding the regions that are conserved in human genome (hg19) have downloaded the multiple sequence alignment of primate. I was examining the file, say, chr1.phyloP46way.primate.wigFix. It is my understanding that each value corresponds to the probability of an nt being conserved at a given position. That is, it must vary from 0 to 1 and 1 being highly conserved.
But examining the file, it has negative value such as -2.34 etc... Any help will be appreciated. Thanks --raja -- Raja Loganantharaj Ph.D. Bioinformatics Scientists National Institute of Environmental Health Science MDA3-01, Research Triangle Park, NC 27709 919-541-9023 _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
