Dear all, I "Arun H Patil", an intern at the "Institute of Bioinformatics and Applied Biotechnology" (IBAB), Bangalore, India. I am working on genomic data & now I am interested in knowing to see if the mutations in the contigs are synonymous/non-synonymous for which I need ORF's (Reading frames) for human genome (HG19). From where and how can I obtain the ORF's of nucleotide sequence for which the protein is already known.
For example, In UCSC genome browser for a gene, nucleotide sequences and its corresponding codons of all the exons are displayed (Attachment contains Screen shot of the above description). Is their any website where I can download this information? -or- Is their any method where I can obtain these results in a flat file? (For example: ftp://hgdownload.cse.ucsc.edu/goldenPath/hg19/database/) Waiting to hear from you. Thanking you, With Regards, Arun H Patil
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