Thanks Brooke,

Best,
Assaf

On Wed, Aug 31, 2011 at 5:13 AM, Brooke Rhead <[email protected]> wrote:

> Hello Assaf,
>
> One of our engineers has this comment for you:
>
> "Many of the other significant hits will be in the chain tables. If there
> is more than one chain for the same region in the reference sequence,
> chances are it is a duplication in the other species. Similarly, to find
> duplications in the reference, the self-chain can be used, or the chains to
> the reference sequence in the other assembly can be used."
>
> Note that the Self Chain table is in the "Variation and Repeats" track
> group, not with the other chains in the "Comparative Genomics" track group.
>  You may also be interested in the pairwise alignment data available for
> download from 
> http://hgdownload.cse.ucsc.**edu/downloads.html<http://hgdownload.cse.ucsc.edu/downloads.html>.
>  Click on the species you are using for reference, then look for the links
> under "Pairwise Alignments."
>
> --
> Brooke Rhead
> UCSC Genome Bioinformatics Group
>
>
>
>
> On 08/28/11 07:12, asas asasa wrote:
>
>> Hi all,
>>
>> About the multiz genomic alignments (I use those downloaded from the table
>> browser in maf format):
>>
>> I understand each aligned sequence represent the "best" hit to the
>> reference
>> genomic segment.Is there a way to compare the best hit to other less
>> significant hits, in order to know whether the best hit is significantly
>> better than other hits ?
>> More generally, my problem is to find a simple way to exclude from my
>> analyses alignments where it is not clear if the aligned sequences are
>> real
>> orthologs.
>>
>> Best,
>> Assaf
>> ______________________________**_________________
>> Genome maillist  -  [email protected]
>> https://lists.soe.ucsc.edu/**mailman/listinfo/genome<https://lists.soe.ucsc.edu/mailman/listinfo/genome>
>>
>
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