Arthur,

Just in case I over explained that... the + strand coordinates are 
listed in the chain file as well. Just see the tStart and tEnd. And 
check here for more info:

http://genome.ucsc.edu/goldenPath/help/chain.html


- Greg


On 11/1/11 2:55 PM, Greg Roe wrote:
> Hi Arthur,
>
> You are not seeing chain ID 439388 (listed at chr2:192280692-192283466)
> in the browser at those coordinates because it is on the negative
> strand.  Note that in chain files (from:
> http://genome.ucsc.edu/goldenPath/help/chain.html), " when the strand
> value is "-", position coordinates are listed in terms of the
> reverse-complemented sequence."
>
> To get the "browser coordinates" (+) from the file (where RC=reverse
> compliment):
>
>       StartRC = qSize - qEnd
>       EndRC = qSize - qStart
>
> So for the chain in question:
>
> chain 63452 chr2 242951149 + 50667683 50670457 chr2 242951149 - 192280692 
> 192283466 439388
>
>
> You would find it here in the browser:
> chr2:50,667,684-50,670,457
>
> Please let us know if you have any additional questions: [email protected]
>
> -
> Greg Roe
> UCSC Genome Bioinformatics Group
>
>
>
>
>
> On 10/31/11 12:45 AM, arthur zhou wrote:
>> dear Sir,
>> I have a problem on the UCSC human genome data about self-chain.
>>
>> I download the data: hg18.hg18.net.gz, hg18.hg18.all.chain.gz,
>> &chr#.hg18.hg18.net.axt.gz
>> through http://hgdownload.cse.ucsc.edu/goldenPath/hg18/vsSelf/.
>>
>> Then I found a position:  chr2:50667684-50670457 in the UCSC Genome
>> Browser. Its self alignment is itself.
>>
>> Then when I check it in the data downloaded, in hg18.hg18.all.chain.gz I
>> just found a position chr2:192280692-192283466, which it said they are a
>> couple of self-chain.
>>
>> But i was surprised to find that I put the
>> position chr2:192280692-192283466 into UCSC Genome Browser, there was no
>> self-chain displayed.
>>
>> Did I download wrong data sets, or maybe there is a updated one needed?
>>
>> I appreciate your reply soon.
>>
>> your sincerely
>>
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