Dear list, I am not sure whether this mailing list was the right place i ask this question, sorry if i am wrong. I want to ask the bigWig files for those bam files in the encode data (for example: http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/, there was wgEncodeBroadHistoneGm12878ControlStdSig.bigWig<http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/wgEncodeBroadHistoneGm12878ControlStdSig.bigWig>, and wgEncodeBroadHistoneGm12878ControlStdAlnRep1.bam<http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/wgEncodeBroadHistoneGm12878ControlStdAlnRep1.bam> , wgEncodeBroadHistoneGm12878ControlStdAlnRep2.bam<http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/wgEncodeBroadHistoneGm12878ControlStdAlnRep2.bam> ) What i want to ask is that how do you generate those bigWig files when replicates exists? Do you use the sum of hits of reads from two bam files? or use the average value? or else?
Appreciated for any response. Best wishes. -- Daofeng _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
