Hi Daofeng,

No, UCSC does not generate these bigWig files. Please contact the data 
provider for more information.

Please let us know if you have any additional questions: 
[email protected]

-
Greg Roe
UCSC Genome Bioinformatics Group


On 11/14/11 12:24 PM, Daofeng Li wrote:
> Hi Vanessa,
>
> Thanks for your response.
> However, i didn't found any descriptions about how the bigWig files were
> generated from the link you provided.
> I also have contacts with some data centers, it seems they only provide
> .bam or .qseq files.
> I think that the bigWig files were generated by UCSC group? am i wrong?
>
> Thanks again.
>
> Best wishes.
>
> On Mon, Nov 14, 2011 at 1:41 PM, Vanessa Kirkup Swing
> <[email protected]>wrote:
>
>> Hi Daofeng,
>>
>> We recommend that you look at the track description page for each track
>> that you are interested in to get the information about how the data was
>> generated. To get to the description page from the downloads page (
>> http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/)
>> there is a link in the README that gives a filterable list of these files:
>>
>> http://genome.ucsc.edu/cgi-bin/hgFileUi?db=hg19&g=wgEncodeBroadHistone
>>
>> Click on the that link. In the upper right hand corner there is a
>> "Description" link that should contain the information that you are looking
>> for. If the description page doesn't answer the questions you have, we
>> recommend that you contact the lab that contributed the data. The contact
>> information for the lab is also provided on the Description Page.
>>
>> If you have further questions, please contact the mailing list:
>> [email protected].
>>
>> Vanessa Kirkup Swing
>> UCSC Genome Bioinformatics Group
>>
>>
>>
>> ---------- Forwarded message ----------
>> From: Daofeng Li<[email protected]>
>> Date: Thu, Nov 10, 2011 at 8:46 PM
>> Subject: [Genome] Question about the encode data
>> To: [email protected]
>>
>>
>> Dear list,
>>
>> I am not sure whether this mailing list was the right place i ask this
>> question, sorry if i am wrong.
>> I want to ask the bigWig files for those bam files in the encode data (for
>> example:
>>
>> http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/
>> ,
>> there was wgEncodeBroadHistoneGm12878ControlStdSig.bigWig<
>> http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/wgEncodeBroadHistoneGm12878ControlStdSig.bigWig
>>> ,
>> and wgEncodeBroadHistoneGm12878ControlStdAlnRep1.bam<
>> http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/wgEncodeBroadHistoneGm12878ControlStdAlnRep1.bam
>> , wgEncodeBroadHistoneGm12878ControlStdAlnRep2.bam<
>> http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeBroadHistone/wgEncodeBroadHistoneGm12878ControlStdAlnRep2.bam
>>   )
>> What i want to ask is that how do you generate those bigWig files when
>> replicates exists?
>> Do you use the sum of hits of reads from two bam files? or use
>> the average value? or else?
>>
>> Appreciated for any response.
>>
>> Best wishes.
>> --
>> Daofeng
>> _______________________________________________
>> Genome maillist  -  [email protected]
>> https://lists.soe.ucsc.edu/mailman/listinfo/genome
>>
>>
>
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