Hello, again, Anelia,

A colleague suggested that you may be interested in dbGap ?

http://www.ncbi.nlm.nih.gov/gap

regards,

                        --b0b kuhn

On 1/20/2012 4:07 PM, robert kuhn wrote:
> Hello, Anelia,
> 
> The whole area of genotype-phenotype associations is fraught with
> technical and ethical difficulties, especially when it comes to
> attempting to diagnose or treat disease.  At the Genome Browser, we
> are not experts in this area and would not attempt to make predictions
> about individual nucleotides.
> 
> Having said that, the OMIM project (omim.org) does have a curated set
> of alleles that we present as a track in the Browser.  It is known as
> the OMIM AV SNPs (AV= Allelic Variant) track and is found in the second
> blue-bar track group beneath the main Browser graphic (Phenotype and 
> Disease Associations).  The data in this track are rather sparse and
> should be used with extreme caution.  It is important to read the entire
> record at omim.org  (follow the link on the details page after clicking 
> an item) carefully before reaching any conclusions.
> 
> You may also be interested to know about the Variant Effect Predictor at
> Ensembl, which makes molecular (not medical!) predictions about the
> affect a variant SNP would have on a protein.
> 
> best wishes in your work and thanks for using the UCSC Genome Browser.
> 
>             --b0b kuhn
>             ucsc genome bioinformatics group
> 
> 
> On 1/20/2012 2:09 PM, Horvath, Anelia (NIH/NICHD) [E] wrote:
>> How can I access data on the phenotype of the individuals with a 
>> certain rare SNP, or at least get the info if they have been 
>> considered healthy controls?
>>
>> Also, is it possible to download the genome/exome data from an 
>> individual with a certain SNP?
>>
>> Thank you so much in advance,
>>
>> Kind regards,
>>
>> Anelia
>>
>>
>> ******************************************
>> Anelia Horvath, PhD
>> NIH/NICHD, PDEGEN
>> 10 Center Dr, CRC, Rm 1E-3216
>> Bethesda, MD 20892
>> Tel: +1 (301) 402 1998
>> Fax:+1(301) 402 0574
>> ******************************************
>>
>> _______________________________________________
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