Since that combination is not supported by BLAT,
swap the target database and query:

blat -t=dnax dna_query.fa -q=prot proteome.fa output.psl

-Galt


On Wed, Jun 27, 2012 at 12:31 PM, Steve Heitner <[email protected]> wrote:

> Hello, Amit.
>
>
>
> Since that combination is not supported by BLAT, go ahead and swap the
> target database and query as in your original email.
>
>
>
> Please contact us again at [email protected] if you have any further
> questions.
>
>
>
> ---
>
> Steve Heitner
>
> UCSC Genome Bioinformatics Group
>
>
>
> From: Amit Pande [mailto:[email protected]]
> Sent: Wednesday, June 27, 2012 2:05 AM
> To: [email protected]
> Subject: Re: [Genome] BLAT - six frames
>
>
>
> Hello Steve,
>
> I already tried what you wrote to me but it gives me the following error:
>
> Loaded 22243362 letters in 51824 sequences
> Unrecognized combination of target and query types
>
> It works if I switch -q with -t, but it wouldn't be correct this
> way....would it ?
>
> warm regards,
> Amit.
>
>
>
>
>
> On Tue, Jun 26, 2012 at 10:29 PM, Steve Heitner <[email protected]>
> wrote:
>
> Hello, Amit.
>
> You were very close.  You just need to reverse your database and query
> options.  The  correct command should be:
>
> blat -t=prot proteome.fa -q=dnax dna_query.fa output.psl
>
> Please contact us again at [email protected] if you have any further
> questions.
>
> ---
> Steve Heitner
> UCSC Genome Bioinformatics Group
>
>
> -----Original Message-----
> From: [email protected] [mailto:[email protected]] On
> Behalf Of Amit Pande
> Sent: Tuesday, June 26, 2012 2:23 AM
> To: [email protected]
> Subject: [Genome] BLAT - six frames
>
> Dear Curators,
>
> I am trying to run BLAT locally on the command line. I have a query file
> which consists of DNA and a database file which has proteome.
> I am using dnax option because I want the query to be translated in 6
> frames
> to protein and then align it to the database.
>
> The command I am typing is:
>
> blat proteome.fa dna_query.fa -t=dnax -q=prot output.psl
>
> I am not sure about the results, kindly tell me whether this is the right
> way to execute the program .
>
> Thank you in advance,
> warm regards,
> Amit.
>
> _______________________________________________
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> https://lists.soe.ucsc.edu/mailman/listinfo/genome
>
>
>
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
>
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