Malaria... a serious concern for Goa. Hardly getting the consistent attention 
it deserves. FN

http://www.scidev.net/gateways/index.cfm?fuseaction=readitem&rgwid=6&item=News&itemid=1851&language=1

Mutation for drug resistance in Indian malaria identified  
 
Aedes aegypti (a vector of Dengue) taking a blood meal through human skin. 
(Courtesy of the Dept. of Medical Illustration, Liverpool School of Tropical 
Medicine, Liverpool, UK). 
T. V. Padma
13 January 2005
Source: SciDev.Net


[AHMEDABAD] Scientists have identified the genetic mutation allowing the 
parasite that causes fatal cerebral malaria in India to resist a widely used 
drug. They warn that India could be becoming a new centre for the spread of 
such resistance, and that it needs to reassess the way it treats the disease.  

The scientists, based at the Indian Institute of Science (IISc) in Bangalore, 
studied the genetic make-up of the malaria parasites in the blood of 200 people 
with cerebral malaria � the form of the disease affecting the brain that 
accounts for almost 60 per cent of the 2.3 million cases of malaria in India 
each year.

The researchers found that in 95 per cent of those infected, the parasite had a 
mutation � termed SVMNT � in one of its genes. Malaria parasites with the 
mutation are not affected by chloroquine, a drug commonly used to treat the 
disease.

Govindrajan Padmanabhan, scientist emeritus at IISc, told the 92nd Indian 
Science Congress in Ahmedabad last week that until now the mutation had not 
been reported outside South America, including in India's neighbouring 
South-East Asia, or in Africa where malaria is rampant.

------------------------------------------------------------------------
Frederick Noronha         784 Near Convent, Sonarbhat SALIGAO GOA India
Freelance Journalist      TEL: +91-832-2409490 MOBILE: 9822122436
http://fn.swiki.net       http://www.livejournal.com/users/goalinks
fred at bytesforall.org   http://www.bytesforall.org


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