The enzyme alcohol dehydrogenase (ADH) which breaks down alcohol in the body is:
Less in women compared to men; hence alcohol stays in the blood a lot longer. 
Less in Asians compared to Whites; so Asian college kids cannot binge-drink 
like White kids.
Decreases as one gets older; so alcohol tolerance decreases with age.
Please read:
http://askdoctork.com/why-cant-women-drink-as-much-as-men-201602198893
Unfortunately women tend to drink a lot more than they did due to:
1.  Increased stress with jobs and family.
2.  Increased earning capacity.
3.  Feminism.
4.  While men are "designated drivers" at a party, women can "have one for the 
road". 

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