You surely get lowest latency for us-central1 if your Redis instance is 
situated in that zone. One of the first steps in setting up Redis for your 
flexible environment is hosting a Redis instance on Google Compute 
Engine.This instance can be located in the zone of your choice. You can 
read more detail on the "Connect to Redis from Node.js on Google App Engine 
Flexible Environment" page 
<https://cloud.google.com/community/tutorials/nodejs-redis-on-appengine>, 
"Start a Redis server" sub-chapter. 

REDIS clusters are only deployed on Compute Engine clusters. They can be 
used by App Engine Flex as its Memcache, since Flex cannot use GAE 
Standard's Google managed Memcache. You can set up your Compute Engine 
Redis instance in a conveniently situated zone, which grants the lowest 
latency, as judging by your planned usage pattern. For instructions on how 
to set up your Redis instance you can check the "How to Set Up Redis on 
Google Compute Engine" online document 
<https://cloud.google.com/community/tutorials/setting-up-redis>.   

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